Applied Genomics and Public Health

George P. Patrinos is Professor of Pharmacogenomics and Pharmaceutical Biotechnology in the University of Patras (Greece), Department of Pharmacy, Head of Division of Pharmacology and Biosciences of the same Department and holds adjunct Full Professorships at Erasmus MC, Faculty of Medicine, Rotterdam (the Netherlands) and the United Arab Emirates University, College of Medicine, Department of Genetics and Genomics, Al-Ain (UAE). Also, since March 2018, he is Chair of the Global Genomic Medicine Collaborative (G2MC) and since May 2023 Chairman of the Scientific Advisory Board of the ASPIRE Abu Dhabi Precision Medicine Research Institute. He has ample regulatory experience, as he served for 12.5 years as Full Member and Greece’s National representative in the CHMP Pharmacogenomics Working Party of the European Medicines Agency (EMA) and he is still an active member of the European Medicines Agency participating in expert panels to provide scientific advice where needed. George is currently Director of the Laboratory of Pharmacogenomics and Individualized Therapy, the first officially established academic pharmacogenomics laboratory in Greece. His group has keen interest in research covering disciplines from wet and dry lab and public health genomics projects, all focusing on pharmacogenomics and personalized medicine. In particular, his research interests involve discovery work and clinical implementation of pharmacogenomics, focusing in particular in psychiatry but also cardiology and oncology, genomics of rare disorders and transcriptional regulation of human fetal globin genes. Moreover, George’s group is internationally recognized for its involvement in developing National/Ethnic Genetic databases to document the genetic heterogeneity in different populations worldwide and of genome informatics tools to translate genomic information into a clinically meaningful format. Also, George’s group has a keen interest in public health genomics to critically assess the impact of genomics to society and public health. George has more than 330 publications in peer-reviewed scientific journals, some of them in leading scientific journals, such as The Lancet and Lancet EBioMedicine. Also, he has co-authored and co-edited more than 15 textbooks, among which the renowned textbook “Molecular Diagnostics”, published by Academic Press, now in its 3rd edition, while he is the editor of “Translational and Applied Genomics” book series, published by Elsevier. Furthermore, since September 2020, he serves as Editor-In-Chief of the prestigious Pharmacogenomics Journal (TPJ), published by Nature Publishing Group, Associate Editor and member of the editorial board of several scientific journals and has been a member of several international boards and advisory and evaluation committees. Apart from that, George is the main co-organizer of the Golden Helix Conferences, an international meeting series on Pharmacogenomics and Genomic Medicine with more than 50 conferences organized in more than 25 countries worldwide.

 Part I 1. Genomic Medicine and Public Health Genomics 2. From Genetic Epidemiology to Exposome and Systems Epidemiology 3. Rare Diseases: Genomics and Public Health 4. Applied Genomics and Public Health Cancer Genomics 5. Genomic basis of psychiatric illnesses and response to psychiatric drug treatment modalities 6. Pharmacogenomics and individualized therapy 7. Microbial genomics in Public Health: A translational risk-response aspect 8. Genome informatics pipelines and genome browsers 9. ?ranslational tools and databases in Genomic Medicine 10. Genetic Testing Part II 11. Assessing the stakeholder landscape and stance point on Genomic and Personalized Medicine 12. Healthcare professionals’ awareness and understanding of genomics 13. Genethics and Public Health Genomics 14. Legal aspects of Genomic and Personalized Medicine 15. Genomics, The Internet of Things, Artificial Intelligence and Society 16. Economic evaluation of Genomic and Personalized Medicine interventions: Implications in Public Health 17. Pricing, budget allocation and reimbursement in Genomic Medicine 18. Genetic counseling 19. Defining genetic testing delivery and promotional strategies for Personalized Medicine 20. Regulatory aspects of Genomic Medicine and Pharmacogenomics 21. Genomic Medicine in emerging economies