Single Molecule and Single Cell Sequencing -

Single Molecule and Single Cell Sequencing

Yutaka Suzuki (Herausgeber)

Buch | Hardcover
150 Seiten
2019 | 1st ed. 2019
Springer Verlag, Singapore
978-981-13-6036-7 (ISBN)
160,49 inkl. MwSt
This book presents an overview of the recent technologies in single molecule and single cell sequencing. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform.
This book presents an overview of the recent technologies in single molecule and single cell sequencing. These sequencing technologies are revolutionizing the way of the genomic studies and the understanding of complex biological systems. The PacBio sequencer has enabled extremely long-read sequencing and the MinION sequencer has made the sequencing possible in developing countries. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform.



This volume presents not only an updated overview of these technologies, but also of the related developments in bioinformatics. Without powerful bioinformatics software, where rapid progress is taking place, these new technologies will not realize their full potential. All the contributors to this volume have been involved in the development of these technologies and software and have also made significant progress on their applications.



This book is intended to be of interest to a wide audience ranging from genome researchers to basic molecular biologists and clinicians. 

Yutaka Suzuki, Department of Computational Biology and Medical Sciences, The University of Tokyo, Japan

Chapter1. Strategies for converting RNA to amplifiable cDNA for single-cell RNA sequencing methods.- Chapter2. Integrated Fluidic Circuits for single cell omics and multi-omics applications.- Chapter3. Single-cell DNA-Seq and RNA-Seq in cancer using the C1 system.- Chapter4. Nx1-Seq (Well based Single-Cell Analysis System).- Chapter5. Quantitation of mRNA transcripts and proteins using the BD Rhapsody™ Single-Cell Analysis System.- Chapter6. An Informative Approach to Single-Cell Sequencing Analysis.- Chapter7. Bionano Genome Mapping: High-Throughput, Ultra-Long Molecule Genome Analysis System for Precision Genome Assembly and Haploid-Resolved Structural Variation Discovery.- Chapter8. Informatics for PacBio long reads.- Chapter10. On-site MinION sequencing.

Erscheinungsdatum
Reihe/Serie Advances in Experimental Medicine and Biology ; 1129
Zusatzinfo 51 Illustrations, color; 5 Illustrations, black and white; VI, 150 p. 56 illus., 51 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 155 x 235 mm
Themenwelt Mathematik / Informatik Informatik Theorie / Studium
Informatik Weitere Themen Bioinformatik
Medizin / Pharmazie Medizinische Fachgebiete
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Genetik / Molekularbiologie
Schlagworte Bioinformatics • epigenome • Genome • New sequencing technology • transcriptome
ISBN-10 981-13-6036-7 / 9811360367
ISBN-13 978-981-13-6036-7 / 9789811360367
Zustand Neuware
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