Application of Clinical Bioinformatics (eBook)

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2016 | 1st ed. 2016
VI, 398 Seiten
Springer Netherlands (Verlag)
978-94-017-7543-4 (ISBN)

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This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.



This bookelucidates how genetic, biological and medical information can be applied tothe development of personalized healthcare, medication and therapies. Focusingon aspects of the development of evidence-based approaches in bioinformaticsand computational medicine, including data integration, methodologies, toolsand models for clinical and translational medicine, it offers an essentialintroduction to clinical bioinformatics for clinical researchers andphysicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. XiangdongWang is a distinguished Professor of Medicine. He is Director of ShanghaiInstitute of Clinical Bioinformatics, Director of Fudan University Center forClinical Bioinformatics, Deputy Director of Shanghai Respiratory ResearchInstitute, Director of Biomedical Research Center, Fudan University ZhongshanHospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of HealthCare and Biomedical Engineering at Institute of Health Care Engineering withEuropean Notified Body of Medical Devices, Graz University of Technology, Graz,Austria; Dr. Denis Shields is a Professor of ClinicalBioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Dengis a Professor at Department of Biostatistics and Bioinformatics, Tulane UniversitySchool of Public Health and Tropical Medicine, USA; Dr. Jacques SBeckmann is a Professor and Director of Section of Clinical Bioinformatics,Swiss Institute of Bioinformatics, Switzerland.



The Era of Big Data: From Data-driven Research to Data-driven Clinical
Care.- Biostatistics, data mining and computational modeling.- Gene expression
and profiling.- The next generation sequencing and
applications in clinical research.- Clinical epigenetics and epigenomics.- Proteomic
profiling: Data mining and analyses.- Targeted metabolomics: the next
generation of clinical chemistry!?.- Clinical bioinformatics for biomarker
discovery in targeted metabolomics.- Metagenomic Profiling, Interaction of
Genomics with Meta-genomics.- Clinical Epigenetics and Epigenomics.- Integrative
Biological Databases.- Standards and Regulations for (Bio)Medical Software.- Clinical
applications and systems biomedicine.- Key Law and Policy Considerations for
Clinical Bioinformaticians.- Challenges and Opportunities in Clinical
Bioinformatics.- Heterogeneity of Hepatocellular Carcinoma.

Erscheint lt. Verlag 31.3.2016
Reihe/Serie Translational Bioinformatics
Zusatzinfo VI, 398 p. 120 illus., 70 illus. in color.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Informatik Weitere Themen Bioinformatik
Medizin / Pharmazie Studium
Naturwissenschaften Biologie
Technik
Schlagworte clinical bioinformatics • clinical epigenetics and epigenomics • data-driven clinical care • gene expression • Systems Biomedicine
ISBN-10 94-017-7543-5 / 9401775435
ISBN-13 978-94-017-7543-4 / 9789401775434
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