Molecular Analysis and Genome Discovery

Preface.List of Contributors1. Pharmacogenetics and Pharmacogenomics: An Overview (W. Kalow).2. Quantitative TaqMan Real-time PCR: Diagnostic and Scientific Applications (Jorg Dotsch, Ellen Schoof and Wolfgang Rascher).3. Hybridization Probes for Real-time PCR (Elaine Lyon).4. An Overview of Genotyping and Single Nucleotide Polymorphisms (SNP) (Ivo Glynne Gut).5. High-throughput Mutation Screening (Paal Skytt Andersen and Lars Allan Larsen).6. Determination of Nucleic Acid Sequence by Pyrosequencing (Elaine Elahi and Mostafa Ronaghi).7. An Introduction to DNA Chips (Magdalena Gabig-Ciminska and Andrzej Ciminski).8. Overview of Microarrays in Genomic Analysis (Janette K Burgess).9. Overview of Differential Gene Expression by High-throughput Analysis (Kin-Ying To).10. Aptamers: Powerful Molecular Tools for Therapeutics and Diagnostics (Eva Baldrich i Rubio, Monica Campas i Homs and Ciara K. O'Sullivan).11. Chip-based Proteomics Technology (Mikhail Soloviev, Richard Barry and Jon Terrett).12. Infectomics Overview: Holistic and Integrative Studies of Infectious Diseases (Sheng-He Huang and Ambrose Jong).13. The Drug Discovery Process (Roberto Solari).14. Structure-based Drug Discovery (Chen-Chen Kan, Kevin Hambly and Derek A. Debe).15. Protein Interaction-targeted Drug Discovery (Gary Hudes, Sanjay Menon and Erica A. Golemis).16. Overview of Quantitative Structure-Activity Relationships (QSAR)(David A. Winkler).Index.