Cell Kinetic Modelling and the Chemotherapy of Cancer
Springer Berlin (Verlag)
978-3-540-50153-4 (ISBN)
I. Mathematical models of cell populations.- 1. Proliferation and differentiation of cells.- 2. The cell cycle.- 3. The simple model of tumor growth.- 4. The extended model of tumor growth.- 5. Cell age distribution and phase indices.- 6. The general model with distributed cycle time.- 7. The Kendall-Takahashi model.- II. Determination of cell kinetic parameters.- Introduction: Cell kinetic experiments.- III. Cell kinetics and cancer therapy.- 1. The surviving fraction after a single dose.- 2. Phase-specific cell kill.- 3. Block of the cell cycle.- 4. Recruitment of resting cells.- 5. A complex mathematical model and computer programs.- 6. Implications for drug testing.- 7. Potential implications for therapy.- 1. Limit theorems for matrix models.- 2. A model with periodic parameters.- 3. Pharmacokinetics and the dose-effect relation.- List of symbols.- References.
Erscheint lt. Verlag | 24.8.1988 |
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Reihe/Serie | Lecture Notes in Biomathematics |
Zusatzinfo | VIII, 157 p. |
Verlagsort | Berlin |
Sprache | englisch |
Maße | 170 x 244 mm |
Gewicht | 290 g |
Themenwelt | Mathematik / Informatik ► Mathematik |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
Schlagworte | Algebra • Cancer • Cancer Research • Cell • cell cycle • Kinetics • Tumor • tumor growth |
ISBN-10 | 3-540-50153-3 / 3540501533 |
ISBN-13 | 978-3-540-50153-4 / 9783540501534 |
Zustand | Neuware |
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