Synthetic Biology (eBook)
XII, 77 Seiten
Springer Netherlands (Verlag)
978-94-017-9382-7 (ISBN)
Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the 'top-down' and 'bottom-up' approaches towards the construction of an artificial cell and the development of the 'iGEM' competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.
Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the 'top-down' and 'bottom-up' approaches towards the construction of an artificial cell and the development of the "e;iGEM"e; competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.
Foreword by Michel MorangePreface1. What is synthetic biology? Engineering ideals and synthetic lifeChallenges for synthetic lifeReferences2. What was synthetic biology? Life and matterSpontaneous generationThe synthesis of living beings a century agoCreating life: utopia and propagandaReferences3. What is life? Why wonder what life is? A single example of lifeReal is a small part of the possibleExtant is a clue for the extinctIndividual and collective lifeBeing alive and being a living beingAwakening from the Cartesian dreamReferences4. Strategies for making lifeFrankenstein and Werker: two strategies to make a living beingÀ la Frankenstein: artificial synthesis of life or the top-down approachÀ la Werker: synthesis of artificial life or the bottom-up approachSynthesizing life as we do not know itReferences5. Synthetic biology in actionVirus and malaria to begin withPlaying God with a chromosome? Cell circuitryCooling down the cool engineerBiofuelsArmpit cheese or public-oriented research in the name of synthetic biologyBeyond practical usesReferences6. The iGEM competitioniGEM –synthetic biology for the youngest scientistsFrom Briobrick to JamboreeThe outcome and the futureReferences7. Are we doing synthetic biology? A word on genomes: are we true writers? Is life engineerable? Standards in biology –the iGEM competitionReferencesPostface by Ricard SoléOnomastic indexSubject index
| Erscheint lt. Verlag | 9.9.2014 |
|---|---|
| Reihe/Serie | SpringerBriefs in Biochemistry and Molecular Biology | SpringerBriefs in Biochemistry and Molecular Biology |
| Zusatzinfo | XII, 77 p. 24 illus., 21 illus. in color. |
| Verlagsort | Dordrecht |
| Sprache | englisch |
| Themenwelt | Informatik ► Grafik / Design ► Digitale Bildverarbeitung |
| Mathematik / Informatik ► Informatik ► Theorie / Studium | |
| Medizin / Pharmazie ► Studium | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| Schlagworte | Artificial Life • Biotechnology • Entomology • Genetic Engineering • Metabolic Engineering • Minimal Cell • Synthetic biology |
| ISBN-10 | 94-017-9382-4 / 9401793824 |
| ISBN-13 | 978-94-017-9382-7 / 9789401793827 |
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