Bayesian Evolutionary Analysis with BEAST - Alexei J. Drummond, Remco R. Bouckaert

Bayesian Evolutionary Analysis with BEAST

Buch | Hardcover
260 Seiten
2015
Cambridge University Press (Verlag)
978-1-107-01965-2 (ISBN)
63,55 inkl. MwSt
A comprehensive overview of Bayesian approaches to phylogenetics using Markov chain Monte Carlo (MCMC) methods, offering theoretical insight, pragmatic advice and tools to develop further models. This title is a one-stop reference to applying the latest phylogenetic models in BEAST 2, interpreting the analyses and extending these models further.
What are the models used in phylogenetic analysis and what exactly is involved in Bayesian evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you choose and apply these models, which parameterisations and priors make sense, and how can you diagnose Bayesian MCMC when things go wrong? These are just a few of the questions answered in this comprehensive overview of Bayesian approaches to phylogenetics. This practical guide: • Addresses the theoretical aspects of the field • Advises on how to prepare and perform phylogenetic analysis • Helps with interpreting analyses and visualisation of phylogenies • Describes the software architecture • Helps developing BEAST 2.2 extensions to allow these models to be extended further. With an accompanying website providing example files and tutorials (http://beast2.org/), this one-stop reference to applying the latest phylogenetic models in BEAST 2 will provide essential guidance for all users – from those using phylogenetic tools, to computational biologists and Bayesian statisticians.

Alexei J. Drummond is Professor of Computational Biology and Principal Investigator at the Allan Wilson Centre of Molecular Ecology and Evolution at the University of Auckland, New Zealand. He is the lead author of the BEAST software package and has gained a reputation in the field as one of the most knowledgeable experts for Bayesian evolutionary analyses. Remco R. Bouckaert is a computer scientist with a strong background in Bayesian methods. He is the main architect of version 2 of BEAST and has been working on extensions to the BEAST software and other phylogenetics projects in Alexei Drummond's group at the University of Auckland.

Preface; Acknowledgements; Part I. Theory: 1. Introduction; 2. Evolutionary trees; 3. Substitution and site models; 4. The molecular clock; 5. Structured trees and phylogeography; Part II. Practice: 6. Bayesian evolutionary analysis by sampling trees; 7. Setting up and running a phylogenetic analysis; 8. Estimating species trees from multilocus data; 9. Advanced analysis; 10. Posterior analysis and post-processing; 11. Exploring phylogenetic tree space; Part III. Programming: 12. Getting started with BEAST; 13. BEAST XML; 14. Coding and design patterns; 15. Putting it all together; Bibliography; List of authors; List of subjects.

Erscheint lt. Verlag 6.8.2015
Zusatzinfo 2 Tables, color; 7 Tables, black and white; 3 Halftones, unspecified; 53 Halftones, color; 18 Line drawings, unspecified; 17 Line drawings, color
Verlagsort Cambridge
Sprache englisch
Maße 180 x 250 mm
Gewicht 680 g
Themenwelt Informatik Weitere Themen Bioinformatik
Mathematik / Informatik Mathematik Computerprogramme / Computeralgebra
Naturwissenschaften Biologie Evolution
Naturwissenschaften Biologie Genetik / Molekularbiologie
ISBN-10 1-107-01965-6 / 1107019656
ISBN-13 978-1-107-01965-2 / 9781107019652
Zustand Neuware
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