Statistical Methods in Spatial Epidemiology (eBook)

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2013 | 2. Auflage
424 Seiten
John Wiley & Sons (Verlag)
978-0-470-03578-8 (ISBN)

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Statistical Methods in Spatial Epidemiology - Andrew B. Lawson
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Spatial epidemiology is the description and analysis of the
geographical distribution of disease. It is more important now than
ever, with modern threats such as bio-terrorism making such
analysis even more complex. This second edition of Statistical
Methods in Spatial Epidemiology is updated and expanded to
offer a complete coverage of the analysis and application of
spatial statistical methods. The book is divided into two main
sections: Part 1 introduces basic definitions and terminology,
along with map construction and some basic models. This is expanded
upon in Part II by applying this knowledge to the fundamental
problems within spatial epidemiology, such as disease
mapping, ecological analysis, disease clustering,
bio-terrorism, space-time analysis,
surveillance and infectious disease modelling.

* Provides a comprehensive overview of the main statistical
methods used in spatial epidemiology.

* Updated to include a new emphasis on bio-terrorism and disease
surveillance.

* Emphasizes the importance of space-time modelling and outlines
the practical application of the method.

* Discusses the wide range of software available for analyzing
spatial data, including WinBUGS, SaTScan and R, and features an
accompanying website hosting related software.

* Contains numerous data sets, each representing a different
approach to the analysis, and provides an insight into various
modelling techniques.

This text is primarily aimed at medical statisticians,
researchers and practitioners from public health and epidemiology.
It is also suitable for postgraduate students of statistics and
epidemiology, as well professionals working in government
agencies.

Professor Andrew B. Lawson is a respected and well-known academic. He has published many papers in leading journals, and a number of books on spatial statistics, including five for Wiley.

Preface and Acknowledgements to Second Edition.

Preface and Acknowledgements.

I: The Nature of Spatial Epidemiology.

1. Definitions, Terminolgy and Data Sets.

1.1 Map Hypotheses and Modelling Approaches.

1.2 Definitions and Data Examples.

1.3 Further definitions.

1.4 Some Data Examples.

2.Scales of Measurement and Data Availability.

2.1 Small Scale.

2.2 Large Scale.

2.3 Rate Dependence.

2.4 DataQuality and the Ecological Fallacy.

2.5 Edge E.ects.

3.Geographical Representation and Mapping.

3.1 Introduction and Definitions.

3.2 Maps and Mapping.

3.3 Statistical Accuracy.

3.4 Aggregation.

3.5 Mapping Issues related toAggregated Data.

3.6 Conclusions.

4.Basic Models.

4.1 Sampling Considerations.

4.2 Likelihood-based and Bayesian Approaches.

4.3 Point EventModels.

4.4 CountModels.

5.Exploratory Approaches, Parametric Estimation andInference.

5.1 ExploratoryMethods.

5.2 Parameter Estimation.

5.3 Residual Diagnostics.

5.4 Hypothesis Testing.

5.5 Edge E.ects.

II:Important Problems in Spatial Epidemiology.

6.Small Scale: Disease Clustering.

6.1 Definition of Clusters and Clustering.

6.2 Modelling Issues.

6.3 Hypothesis Tests for Clustering.

6.4 Space-Time Clustering.

6.5 Clustering Examples.

6.6 OtherMethods related to clustering.

7.Small Scale: Putative Sources of Hazard.

7.1 Introduction.

7.2 StudyDesign.

7.3 Problems of Inference.

7.4 Modelling the Hazard Exposure Risk.

7.5 Models for Case Event Data.

7.6 ACase Event Example.

7.7 Models for CountData.

7.8 ACountData Example.

7.9 OtherDirections.

8. Large Scale: Disease Mapping.

8.1 Introduction.

8.2 Simple Statistical Representation.

8.3 BasicModels.

8.4 AdvancedMethods.

8.5 Model Variants and Extensions.

8.6 ApproximateMethods.

8.7 MultivariateMethods.

8.8 Evaluation ofModel Performance.

8.9 Hypothesis Testing in DiseaseMapping.

8.10 Space-Time DiseaseMapping.

8.11 Spatial Survival and longitudinal data.

8.12 DiseaseMapping: Case Studies.

9.Ecological Analysis and Scale Change.

9.1 Ecological Analysis: Introduction.

9.2 Small-ScaleModelling Issues.

9.3 Changes of Scale andMAUP.

9.4 A Simple Example: Sudden Infant Death in North Carolina.

9.5 ACase Study: Malaria and IDDM.

10.Infectious Disease Modelling.

10.1 Introduction.

10.2 GeneralModelDevelopment.

10.3 SpatialModelDevelopment.

10.4 Modelling Special Cases for Individual Level Data.

10.5 Survival Analysis with spatial dependence.

10.6 Individual level data example.

10.7 Underascertainment and Censoring.

10.8 Conclusions.

11.Large Scale: Surveillance.

11.1 Process ControlMethodology.

11.2 Spatio-Temporal Modelling.

11.3 Spatio-TemporalMonitoring.

11.4 Syndromic Surveillance.

11.5 Multivariate-Mulitfocus Surveillance.

11.6 Bayesian Approaches.

11.7 Computational Considerations.

11.8 Infectious Diseases.

11.9 Conclusions.

Appendix A:Monte Carlo Testing, Parametric Bootstrap andSimulation Envelopes.

Appendix B:Markov ChainMonte Carlo Methods.

Appendix C:Algorithms and Software.

Appendix D: Glossary of Estimators.

Appendix E:Software.

Bibliography.

Index.

"...the second edition is a substantial improvement on what was already a valuable, well structured and comprehensive reference..." (Biometrics, September 2007)

Erscheint lt. Verlag 23.5.2013
Reihe/Serie Wiley Series in Probability and Statistics
Sprache englisch
Themenwelt Mathematik / Informatik Mathematik Statistik
Mathematik / Informatik Mathematik Wahrscheinlichkeit / Kombinatorik
Medizin / Pharmazie Allgemeines / Lexika
Studium Querschnittsbereiche Epidemiologie / Med. Biometrie
Schlagworte Allg. Public Health • Arbeitssicherheit u. Umweltschutz i. d. Chemie • biometrics • Biometrie • Biostatistics • Biostatistik • Chemical and Environmental Health and Safety • Chemie • Chemistry • Epidemiologie • Gesundheits- u. Sozialwesen • Health & Social Care • Public Health General • Statistics • Statistik
ISBN-10 0-470-03578-1 / 0470035781
ISBN-13 978-0-470-03578-8 / 9780470035788
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