Microarray Gene Expression Data Analysis (eBook)

Helen Causton is an experimental biologist who carried out some of the early studies on genome-wide transcriptional regulation in yeast using microarrays. She is Head of the Clinical Sciences Microarray Centre at Imperial College, University of London. John Quackenbush is a principal investigator at The Institute for Genomic Research (TIGR). His research interests include development of software for microarray data analysis, gene indices and comparative genomics. Alvis Brazma is a computer scientist who has been involved in microarray data analysis since 1998. He heads microarray informatics at the European Bioinformatics Institute and is in charge of establishing a public repository for microarray data.

Preface.

Acknowledgements.

Part I: Introduction:.

1. What Are Microarrays?.

2. Use Of Icroarrays To Monitor Gene Expression.

3. Other Uses For Microarrays.

4. Challenges Associated With The Generation Of Large Amounts Of
Complex Data.

5. Future Directions.

Part II: Aspects Of Experimental Design:.

6. Features Of Microarray Data.

7. Designing The Best Experiment.

8. Preparation of Target.

9. Design of Spotted Arrays.

10. Hybridisation.

11. Long Term Considerations.

12. Verification of Results.

Part III: Data Analysis:.

13. Preliminary Processing of Data.

14. Methods for Data Analysis.

15. Graph Models.

16. Software In The Public Domain.

17. Visualisation of Data.

Part IV: Glossary:.

Index.

Colour plates fall between pp. 84 and 85.