Bioinformatics (eBook)

Dr. Baxevanis is Associate Director for Intramural Research, and Director for Computational Genomics at the National Human Genome Research Institute, National Institutes of Health. He received his BS in biological sciences from Cornell University in 1984 and his PhD in the Department of Biology at The Johns Hopkins University in 1991. His research focuses on protein structure-function relationships, positional cloning, and the development of new methods for analysis of gene expression data. His accom-plishments have been recognized by the Bodossaki Foundation in Greece, who awarded him their 1999 Academic Prize in Medicine and Biology. Dr. Ouellette is Director of the Bioinformatics Core facility at the Center for Molecular Medicine and Therapeutics, University of British Columbia, and Director of the Bioinformatics Core facility for the Canadian Genetic Diseases Network. He held the position of GenBank coordinator for the National Center for Biotechnology Information at the National Institutes of Health. He received his PhD from the Department of Biology at McGill University in 1991, and is the founder and moderator of bionet.molbio.yeast, a Usenet discussion forum for the yeast genomics community.

Bioinformatics and the Internet (A. Baxevanis & B. Ouellette).

The NCBI Data Model (J. Ostell, et al.).

The GenBank Sequence Database (I. Karsch-Mizrachi & B.
Ouellette).

Submitting DNA Sequences to the Databases (J. Kans & B.
Ouellette).

Structure Databases (C. Hogue).

Genomic Mapping and Mapping Databases (P. White & T.
Matise).

Information Retrieval from Biological Databases (A.
Baxevanis).

Sequence Alignment and Database Searching (G. Schuler).

Multiple Sequence Alignment (G. Barton).

Predictive Methods Using DNA Sequences (A. Baxevanis).

Predictive Methods Using Protein Sequences (S. Banerjee-Basu
& A. Baxevanis).

Expressed Sequence Tags (ESTs) (T. Wolfsberg & D.
Landsman).

Sequence Assembly and Finishing Methods (R. Staden, et
al.).

Phylogenetic Analysis (F. Brinkman & D. Leipe).

Comparative Genome Analysis (M. Galperin & E. Koonin).

Large-Scale Genome Analysis (P. Meltzer).

Using Perl to Facilitate Biological Analysis (L. Stein).

"...a well-written and organized guide to mining and analyzing
both the mounts of publicly available genetic and protein data as
well as one's own data sets...an excellent reference for a
wide range of techniques." (American Journal of Physical
Anthropology, May 2005)

"...can be used as a classroom text, a tutorial, or a laboratory
bench reference...reinforces concepts that have survived...and
incorporates new approaches and algorithms for analyzing genes and
proteins." (SciTech Book News, Vol. 25, No. 3, September
2001)

"...a great book covering the discipline of bioinformatics....
This high quality book will be helpful to many..." (Lab
News, October/November 2001)

"Baxevanis and Ouellette provide a timely update and much new
information in this important field. Although each chapter has been
revised and updated, the strengths of the first edition remain. The
range of topics is comprehensive.... Each topic is presented in an
easily accessible style.... An important feature is the frequent
discussion of the shortcomings and pitfalls.... A surprising
addition, and one that is also surprisingly lucid, practical and
even entertaining, is the chapter on Perl programming.... It is
most highly recommended for students and for established
investigators alike...." (Trends in Genetics)

"[it] is a good practical book and many will benefit from
reading it" (Proteomics, May 25, 2001)

"...beneficial to both beginners and experienced readers...this
book, written by the top scientists in the field of bioinformatics,
is the perfect choice for every molecular biology laboratory"
(The Quarterly Review of Biology, March 2002)

"A useful introduction to biologists, with a particularly strong
introduction to the tools available from the NCBI."

--Russ B. Altman, MD, PhD, Stanford University Medical Center