Genome-Wide Association Studies and Genomic Prediction
Humana Press Inc. (Verlag)
978-1-62703-446-3 (ISBN)
R for Genome-Wide Association Studies.- Descriptive Statistics of Data: Understanding the Data Set and Phenotypes of Interest.- Designing a Genome-Wide Association Studies (GWAS): Power, Sample Size, and Data Structure.- Managing Large SNP Datasets with SNPpy.- Quality Control for Genome-Wide Association Studies.- Overview of Statistical Methods for Genome-Wide Association Studies (GWAS).- Statistical Analysis of Genomic Data.- Using PLINK for Genome-Wide Association Studies (GWAS) and Data Analysis.- Genome-Wide Complex Trait Analysis (GCTA): Methods, Data Analyses, and Interpretations.- Bayesian Methods Applied to Genome-Wide Association Studies (GWAS).- Implementing a QTL Detection Study (GWAS) Using Genomic Prediction Methodology.- Genome-Enabled Prediction Using the BLR (Bayesian Linear Regression) R-Package.- Genomic Best Linear Unbiased Prediction (gBLUP) for the Estimation of Genomic Breeding Values.- Detecting Regions of Homozygosity to Map the Cause of Recessively Inherited Disease.- Use of Ancestral Haplotypes in Genome-Wide Association Studies.- Genotype Phasing in Populations of Closely Related Individuals.- Genotype Imputation to Increase Sample Size in Pedigreed Populations.- Validation of Genome-Wide Association Studies (GWAS) Results.- Detection of Signatures of Selection Using FST.- Association Weight Matrix: A Network-Based Approach Towards Functional Genome-Wide Association Studies.- Mixed Effects Structural Equation Models and Phenotypic Causal Networks.- Epistasis, Complexity, and Multifactor Dimensionality Reduction.- Applications of Multifactor Dimensionality Reduction to Genome-Wide Data Using the R Package ‘MDR’.- Higher Order Interactions:Detection of Epistasis Using Machine Learning and Evolutionary Computation.- Incorporating Prior Knowledge to Increase the Power of Genome-Wide Association Studies.- Genomic Selection in Animal Breeding Programs.
Reihe/Serie | Methods in Molecular Biology ; 1019 |
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Zusatzinfo | 31 Illustrations, color; 36 Illustrations, black and white; XI, 566 p. 67 illus., 31 illus. in color. With online files/update. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Informatik ► Weitere Themen ► Bioinformatik |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | computational methods • Genome Analysis • Genome-wide association study • Genomic prediction • GWAS • Phenotypic outcomes • Statistical approaches |
ISBN-10 | 1-62703-446-3 / 1627034463 |
ISBN-13 | 978-1-62703-446-3 / 9781627034463 |
Zustand | Neuware |
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