DNA Interactions with Polymers and Surfactants (eBook)

A broad overview of the interaction of DNA with surfactants and
polymers

Due to the potential benefits of biotechnology, interest in the
interaction between DNA and surfactants and polymers has become
increasingly significant. Now, DNA Interactions with Polymers
and Surfactants provides an extensive, up-to-date overview of
the subject, giving readers a basis for understanding the factors
leading to complexation between DNA and different cosolutes,
including metal ions, polyelectrolytes, spermine, spermidine,
surfactants and lipids, and proteins.

Topical coverage includes:

* Polyelectrolytes, physico-chemical aspects and biological
significance

* Solution behavior of nucleic acids

* Single DNA molecules: compaction and decompaction

* Interaction of DNA with surfactants and cationic polymers

* Interactions of histones with DNA

* DNA-DNA interactions

* The hydration of DNA-amphiphile complexes

* DNA-surfactant/lipid complexes at liquid interfaces

* DNA and DNA-surfactant complexes at solid surfaces

* The role of correlation forces for DNA-cosolute interactions

* Simulations of polyions

* Cross-linked DNA gels and gel particles

* DNA as an amphiphilic polymer

* Lipid-DNA interactions

Covering both theoretical and practical aspects of the subject,
DNA Interactions with Polymers and Surfactants is an ideal
resource for chemists and biochemists working in gene and DNA
delivery research in industry and academia, as well as for cell
biologists, chemical engineers, molecular biologists, and
development biologists in the pharmaceutical industry.