Evolutionary Genomics and Systems Biology (eBook)

A comprehensive, authoritative look at an emergent area in
post-genomic science, Evolutionary genomics is an up-and-coming,
complex field that attempts to explain the biocomplexity of the
living world. Evolutionary Genomics and Systems Biology is
the first full-length book to blend established and emerging
concepts in bioinformatics, evolution, genomics, and structural
biology, with the integrative views of network and systems biology.

Three key aspects of evolutionary genomics and systems biology
are covered in clear detail: the study of genomic history, i.e.,
understanding organismal evolution at the genomic level; the study
of macromolecular complements, which encompasses the evolution of
the protein and RNA machinery that propels life; and the
evolutionary and dynamic study of wiring
diagrams--macromolecular components in interaction--in
the context of genomic complements. The book also features:

* A solid, comprehensive treatment of phylogenomics, the
evolution of genomes, and the evolution of biological networks,
within the framework of systems biology

* A special section on RNA biology--translation, evolution
of structure, and micro RNA and regulation of gene expression

* Chapters on the mapping of genotypes to phenotypes, the role of
information in biology, protein architecture and biological
function, chromosomal rearrangements, and biological networks and
disease

* Contributions by leading authorities on each topic

Evolutionary Genomics and Systems Biology is an ideal
book for students and professionals in genomics, bioinformatics,
evolution, structural biology, complexity, origins of life,
systematic biology, and organismal diversity, as well as those
individuals interested in aspects of biological sciences as they
interface with chemistry, physics, and computer science and
engineering.