Lipoprotein Metabolism and Atherogenesis
Springer Verlag, Japan
978-4-431-68426-8 (ISBN)
1: The Molecular Approach to Risk Factors and Prevention.- Lipoprotein Metabolism and Atherogenesis.- Role of Lipid Concentrations and Apolipoproteins in Altering ApoB Metabolism and Promoting Coronary Events.- Long-Term Effect of LDL-Apheresis on Familial Hypercholesterolemia Homozygotes.- Molecular Mechanism of Visceral Obesity.- Diabetes and Atherosclerosis.- 2: The Molecular Basis of Lipoprotein Metabolism (I).- Molecular Genetics and Clinical Features of Japanese Patients with Familial Hypercholesterolemia.- Molecular Analysis of Apolipoprotein A-I and E Mutants in Japan.- Novel Mutations of the LDL Receptor Gene in Familial Hypercholesterolemia Pedigrees in Hokkaido.- Preheparin Lipoprotein Lipase Mass Might Reflect the Amount of Working Lipoprotein Lipase in the Whole Body.- Quantitative Trait Loci (QTLs) for Serum Cholesterol Levels in the Stroke-Prone Spontaneoulsy Hypertensive Rats (SHRSP).- Evidence of Linkage in Familial Combined Hyperlipidemia to Chromosome lq21-q23.- Molecular Analysis on the LDL Receptors in Two Patients with Homozygous Familial Hypercholesterolemia.- Common Mutation of 5, 10-Methylenetrahydrofolate Reductase Accelerates Coronary Artery Disease in Familial Hypercholesterolemia.- Effect of Troglitazone on Plasma Lipid Metabolism and Lipoprotein Lipase.- Combination of LPL Gene Exon 9 Ser447 ? Ter Nonsense Mutation and Apo ?2 Allele Might Contribute to Development of Hypertriglyceridemia.- Improvement by Thiazolidinediones of Vascular Endothelial Cell Dysfunction in Diabetic Patients: A Possible New Physiological Role of PPAR?.- Beneficial Effect of Gemfibrozil on LDL Chemicophysical Characteristics and Oxidizability.- Inhibitory Effect of HMG-CoA Reductase Inhibitors for the Development and Progression of Intimal-Medial Thickness in Carotid Artery in Type 2 Diabetes Mellitus with Hypercholesterolemia.- Plasma Phosphatidylcholine Hydroperoxide Concentrations in Normal Subjects and Patients with Hyperlipidemia.- 3: The Moleculer Basics of Lipoprotein Metabolism (II).- Lipid Transfer Proteins and Receptors in HDL Metabolism.- PPARs and Atherosclerosis.- Molecular Basis of Cellular Cholesterol Efflux and Regulation of Plasma HDL Level.- Roles of Apolipoprotein E Receptors in Lipoprotein Metabolism.- The Structure and Function of the Scavenger Receptor Class A.- Impairment of Reverse Cholesterol Transport System and Atherosclerosis.- ACAT Genes and Proteins in Humans.- Caveolin is Cholesterol-Binding Protein.- In Vivo Functions of SREBPs.- Molecular Characterization of Arachidonate Preferring Acyl-CoA Synthetase, ACS4.- Molecular Characterization of Short-Chain Acyl-CoA Synthetases.- Expression of the VLDL Receptor is Up-Regulated by Cell Differentiation in HL-60 Cells.- Transcriptional Regulation of the Genes for Human HMG CoA Synthase and Squalene Synthase by SREBP and NF-Y.- Expression of Acyl-Coenzyme A: Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages.- Relationship Between Postprandial Triglyceride Level and Intima-Media Thickness of Carotid Artery After Troglitazone Treatment in Type 2 Diabetes.- A New Rabbit Strain with Heritable Hypercholesterolemia and Hypertriglyceridemia.- Turnover of Glutathione and Ascorbic Acid is Suppressed in Hyperlipidemic Rabbits.- Pravastatin, an HMG-CoA Reductase Inhibitor, is Transported by Rat Organic Anion Transporting Polypeptide, oatp2.- 4: The Search for the Link Between Lipoprotein Metabolism Disorder and Atherogenesis (I).- The Puzzling Ligands for Scavenger Receptors.- Granulocyte Macrophage Colony-Stimulating Factor is Involved in Murine Macrophage Proliferation Induced by Oxidized Low Density Lipoprotein.- Mast Cells in Atherogenesis: A Model for Studying Proteolytic Modification of Low and High Density Lipoproteins.- LOX-l, an Endothelial Receptor for Oxidized LDL — Implications for Induction of Endothelium Dysfunction in the Pathogenesis of Vascular Diseases —.- Inducible Expression of Lectin-Like Oxidized Low Density Lipoprotein Receptor-1 in Vascular Endothelial Cells and Macrophages.- Identification and Characterization of a PDZ Domain-Containing Protein that Interacts with the HDL Receptor SR-BI.- Structure and Function of Human SREC (Scavenger Receptor Expressed by Endothelial Cells), A Novel Receptor for Modified LDL.- The Role of CD36 in Atherogenesis as a Receptor for OxLDL.- Apoptosis in Atherosclerosis: Induction of Apoptosis by Oxidized Low Density Lipoprotein and Oxysterols.- Combination Treatment with an Insulin Action Enhancer and an Inhibitor of HMG-CoA Reductase Shows a Synergistic Effect on Atherosclerosis of WHHL Rabbits.- Reduced Secretion of Tumor Necrosis Factor-? and Interleukin-1 ? from Monocyte-Derived Macrophages of CD36-Deficient Subjects in Response to Oxidized LDL.- CD36 Expression in Human Monocytic Leukemia Cell Lines: THP-1 and THP-1 Subtype, Show Different Expressions of Type I and Type II Scavenger Receptors.- 5: The Search for the Link Between Lipoprotein Metabolism Disorder and Atherogenesis (II).- Alteration of Smooth Muscle Cell Phenotype in Diabetic Vascular Wall: From the Molecular Point of View.- The Vascular Nitric Oxide/Superoxide System and Atherosclerosis.- Antagonistic Monoclonal Antibody Against Receptor Tyrosine Kinases: A Novel Strategy to Study the Role of Monocyte/Macrophage in Atherogenesis In Vivo.- Rac l and CDC42Hs Play a Critical Role in MCP-1-Induced Chemotaxis.- Stimulation of Mitogen-Activated Kinases by Lysophosphatidylcholine in Bovine Aortic Endothelial Cells.- Ca2+-Dependent Activation of the 33-kDa Thrombin Receptor-Associated Kinase in Human Platelets.- Lysophosphatidylcholine Generates Superoxide Anios Through Activation of Phosphatidylinositol 3-Kinase in Human Neutrophils.- PDGF Enhanced 7-Ketocholesterol-Induced Apoptosis of Vascular Smooth Muscle Cell, Accompaning with c-myc Expression.- Adventitia-Derived Macrophages Contribute to the Formation of Coronary Arteriosclerotic Lesions in Pigs In Vivo — Potentiating Effect of Oxidative Stress —.- Expression of CD36 in Cultured Human Aortic Smooth Muscle Cells (HASMCs).- Induction of Macrophage VEGF in Response to Oxidized LDL and VEGF Accumulation in Human Atherosclerotic Lesion.- F-1394, an ACAT Inhibitor, Inhibits Neointimal Thickening and Macrophage Accumulation After Balloon Injury in the Cholesterol-Fed Rabbit.- Key Word Index.
Zusatzinfo | XVIII, 283 p. |
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Verlagsort | Tokyo |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 464 g |
Themenwelt | Mathematik / Informatik ► Informatik |
Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie | |
Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
Schlagworte | atherogenesis • atherosclerosis • Lipoprotein Metabolism • risk factors • Vascular Endothelial Cells |
ISBN-10 | 4-431-68426-3 / 4431684263 |
ISBN-13 | 978-4-431-68426-8 / 9784431684268 |
Zustand | Neuware |
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