Statistics Applied to Clinical Trials - Ton J. Cleophas, A.H. Zwinderman

Statistics Applied to Clinical Trials

Buch | Softcover
210 Seiten
2006 | Softcover reprint of the original 2nd ed. 2002
Springer-Verlag New York Inc.
978-1-4020-0570-1 (ISBN)
69,54 inkl. MwSt
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This book not only explains classical statistical analyses of clinical trials, but addresses relatively novel issues, including equivalence testing, interim analyses, sequential analyses, and meta-analyses, and provides a framework of the best statistical methods currently available for such purposes. The book is not only useful for investigators involved in the field of clinical trials, but also for all physicians who wish to better understand the data of trials as currently published.

Preface. Foreword. 1. Hypotheses, Data, Stratification. 2. The analysis of efficacy data of drug trials. 3. The analysis of safety data of drug trials. 4. Equivalence testing. 5. Statistical power and sample size. 6. Interim analysis. 7. Multiple statistical inferences. 8. Principles of linear regression. 9. Subgroup analysis multiple linear regression: confounding, interaction, synergism. 10. Curvilinear regression. 11. Meta-analysis. 12. Crossover studies with continuous variables: power analysis. 13. Crossover studies with binary responses. 14. Post-hoc analysis in clinical trials, a case for logistic regression analysis. 15. quality-of-life assessment in clinical trials. 16. Statistics for the analysis of genetic data. 17. Relationship among statistical distributions. 18. Statistics is not "bloodless" algebra. Appendix. Index.

Erscheint lt. Verlag 23.2.2006
Zusatzinfo XIII, 210 p.
Verlagsort New York, NY
Sprache englisch
Maße 160 x 240 mm
Gewicht 720 g
Themenwelt Mathematik / Informatik Mathematik Statistik
Mathematik / Informatik Mathematik Wahrscheinlichkeit / Kombinatorik
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium Querschnittsbereiche Epidemiologie / Med. Biometrie
ISBN-10 1-4020-0570-9 / 1402005709
ISBN-13 978-1-4020-0570-1 / 9781402005701
Zustand Neuware
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