Genes, Chromosomes, and Disease

From Simple Traits, to Complex Traits, to Personalized Medicine

Nicholas Wright Gillham (Autor)

Buch | Hardcover

352 Seiten

2011
Financial Times Prentice Hall (Verlag)
978-0-13-707544-7 (ISBN)

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This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

Nicholas Wright Gillham is James B. Duke Professor of Biology Emeritus. His research interests involved the genetics and molecular biology of cellular organelles called chloroplasts and mitochondria. For more than a decade he taught a course entitled “The Social Implications of Genetics.” This course fostered his interest in eugenics, human genetics, and their history. He has authored two books on chloroplasts and mitochondria plus a biography of the Victorian scientist Francis Galton entitled, A Life of Sir Francis Galton: From African Exploration to the Birth of Eugenics (Oxford University Press, 2001).

Preface     ix

Chapter 1: Hunting for disease genes     1

Chapter 2: How genetic diseases arise     25

Chapter 3: Ethnicity and genetic disease     55

Chapter 4: Susceptibility genes and risk factors     81

Chapter 5: Genes and cancer     103

Chapter 6: Genes and behavior     129

Chapter 7: Genes and IQ: an unfinished story     151

Chapter 8: Preventing genetic disease     175

Chapter 9: Treating genetic disease     199

Chapter 10: The dawn of personalized medicine     235

Postscript: a cautionary note     249

References and notes     253

Glossary     293

Some useful human genetics Web sites     307

Acknowledgments     309

About the author     311

Index     313

Erscheint lt. Verlag	14.7.2011
Verlagsort	Upper Saddle River
Sprache	englisch
Maße	177 x 236 mm
Gewicht	594 g
Themenwelt	Schulbuch / Wörterbuch
	Informatik ► Weitere Themen ► Bioinformatik
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Humanbiologie
ISBN-10	0-13-707544-8 / 0137075448
ISBN-13	978-0-13-707544-7 / 9780137075447
Zustand	Neuware