Fundamentals of Forensic DNA Typing

John M. Butler is a NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has won numerous scientific awards, including being named Science Watch’s #1 world-wide high-impact author in legal medicine and forensic science over the last decade (July 2011). He has over 150 publications in this field and is a frequent presenter on the topic of DNA typing, and has authored four other DNA Typing books including Advanced Topics in Forensic DNA Typing: Methodology. For a detailed CV, visit http://www.cstl.nist.gov/strbase/butler.htm.

Foreword
Introduction
Acknowledgments
About the author

1 Overview and History of DNA Typing
2 Basics of DNA Biology and Genetics
3 Historical Methods
4 Sample Collection, Storage and Characterization
5 DNA Extraction
6 DNA Quantitation
7 DNA Amplification (The Polymerase Chain Reaction)
8 Short Tandem Repeat Markers
9 Fundamentals of DNA separation and Detection
10 STR Genotyping and Data Interpretation
11 Statistical Interpretation: Evaluating the Strength of Forensic DNA Evidence
12 DNA databases
13 Quality Assurance
14 Forensic Challenges: Degraded DNA, Mixtures, and LCN
15 Additional Loci and Non-Human DNA Testing
16 Lineage Markers: Y Chromosome and mtDNA Testing
17 Applications of DNA Typing
18 Future Trends

Appendix
1 Glossary of Terms
2 Useful Websites
3 Probability and Statistics