Intraoperative Mapping of Cognitive Networks

Emmanuel Mandonnet is currently full Professor of neurosurgery at Lariboisiere hospital, University of Paris. After achieving a PhD in physics in 2000, he turned towards medical school and then residency in neurosurgery. His clinical and research activities focus on brain tumors, and especially awake surgery of gliomas. More specifically, the aim of his work is to better predict the functional cognitive impact of surgical resections and to better understand the effect of electrical stimulations at different scales (from neurons to networks). Guillaume Herbet is currently associate Professor of neuropsychology and cognitive neuroscience at University of Montpellier' Department of medicine and clinical neuropsychologist at Gui de Chauliac hospital' Department of Neurosurgery. His clinical activity is led in collaboration with Pr Duffau, and mainly aims to monitor cognitive functions of patients undergoing glioma resections in awake conditions. For almost 10 years, he developed new tasks to map the functional networks underlain by the right hemisphere, in particular with respect to emotion, social and semantic cognition. Guillaume Herbet is especially interested in better understanding the mechanistic aspects of tumor-induced neural plasticity and in disentangling the role of white tracts in cognition and behavior.

Foreword.- Preface.- Part I: Sensorimotor and visuo-spatial functions.- 1. Motor control.- 2. Vision.- 3. FEF.- 4. Spatial cognition.- Part II: Language functions.- 5. Lexical access.- 6. Spontaneous speech.- 7. Reading.-  8. Writing.- 9. Repeating.- 10. Syntactic abilities.- 11. Verbs versus nouns naming.- 12. Verbal short-term memory.- 13. Proper names retrieval.- 14. Bilingual patients.- Part III: Higher-order functions.- 15. From verbal to non-verbal semantics.- 16. Inhibition.- 17. Set-shifting.- 18. Social cognition.- 19. Multitask mapping.- Part IV: Prospects.- 20. Creativity.- 21. Psychiatric and behavorial traits.- 22. Awake surgery in patients with poor abilities of verbal communication.- 23. Can we map inner speech?.- 24. Beyond tasks: when experience shapes intuition.