5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part B

Prof. Giuseppe Di Giovanni received his Ph.D. in Neuroscience from the University of Chieti, Italy and was a postdoctoral fellow at Yale University, USA. Previously Senior Lecturer of Human Physiology at the Faculty of Medicine and Surgery, University of Palermo, and Associate Professor at the University of Malta, from 2013 he is Professor of Human Physiology at the Medical School of the University of Malta and from 2018 Honorary Professor at Cardiff University, UK. His research focuses on understanding the pathophysiology of monoaminergic systems using electrophysiological and neurochemical approach. He has published more than 120 peer-reviewed papers, edited 7 books and 6 special issues of various journals. Professor Philippe De Deurwaerdère, Centre National de la Recherche Scientifique Bordeaux Cedex France

Part 1: Serotonin in the CNS 1. The multiple facets of serotonergic modulation on brain functions Giuseppe Di Giovanni 2. Anatomical and neurochemical organization of the serotonergic system in the mammalian brain Harry Steinbusch 3. 5-HT2A/2C Receptors in the Brain Cristiano Bombardi

Part 2: Serotonin-dopamine interactions 4. Electrophysiological and neurochemical bases for an interaction of serotonin on central dopaminergic neurons Giuseppe Di Giovanni 5. The complex nature of serotonin-dopamine neurons interaction in primate model of Parkinson’s disease Véronique Sgambato 6. The status of serotonergic system in presymptomatic and symptomatic stages of Huntington disease and corresponding animal models Anthony Hannan 7. Serotonin–dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias Manolo Carta 8. The serotonergic agent L-DOPA in the treatment of Parkinson’s disease Marios Politis

Part 3: Serotonin-Glutamate interaction 9. Cortical influences of serotonin on pyramidal cells Gerard Joseph Marek 10. The interaction of serotonin with noradrenergic, dopaminergic, cholinergic, and opioid systems in Alzheimer's disease Goran Simic 11. Serotonergic controls upon the glutamatergic neurons of the subthalamic nucleus Luisa Ugedo