Marijuana and Madness

David Castle is Chair of Psychiatry, St Vincent's Hospital and the University of Melbourne. Sir Robin M. Murray is Professor of Psychiatric Research, Institute of Psychiatry, and Honorary Consultant, South London and Maudsley NHS Foundation Trust, London. Deepak Cyril D'Souza is Associate Professor of Psychiatry, Director, Schizophrenia Research Program VACHS, and Director, VA-CMHC Schizophrenia Research Clinic, Yale University, Connecticut.

Foreword; Preface; Part I. Pharmacology of Cannabis and the Endocannabinoid System: 1. The cannabinoid system from the point of view of a chemist Raphael Mechoulam and Lumir Hanus; 2. The function of the endocannabinoid system Roger Pertwee; 3. How cannabis works in the brain Leslie Iversen; Part II. The Changing Face of Cannabis: 4. The epidemiology of cannabis use: an international perspective Sandeep Chawla; 5. Is cannabis becoming more potent? Mahmoud ElSohly and David Potter; 6. Health policy and cannabis Wayne Hall and Louisa Degenhardt; Part III. Cannabis and the Brain: 7. Cannabis, endocannabinoids and neurodevelopment Ismael Galve-Roperh; 8. The impact of pubertal exposure to cannabis on the brain: a focus on animal studies Miriam Schneider; 9. Cannabis and cognition: short and long-term effects Nadia Solowij; 10. Does cannabis cause lasting brain damage? Nadia Solowij, Murat Yucel, Valentina Lorenzetti and Dan Lubman; Part IV. Cannabis, Anxiety and Mood: 11. Acute and subacute psychiatric effects of cannabis David Castle and Nadia Solowij; 12. The association between cannabis use and depression Louisa Degenhardt, Wayne Hall, Michael Lynskey, Carolyn Coffey and George Patton; 13. Cannabis and bipolar disorder Carol Silberberg and David Castle; Part V. Cannabis and Psychosis: 14. Cannabis and psychosis proneness Jim van Os, Helene Verdoux and David Castle; 15. Genetic factors that moderate the psychomimetic effects of cannabis Marta Di Forti, Robin M. Murray and Cecile Henquet; 16. Cannabis causes positive, negative, cognitive symptoms and produces impairments in electrophysiological indices of information processing Mohini Ranganathan, Andrew Sewell, Daniel Mathalon and Deepak Cyril D'Souza; 17. The neural basis for the acute effects of cannabis on learning and psychosis Sagnik Bhattacharrya and Phil McGuire; Part VI. Cannabinoids and Schizophrenia: Aetiopathology and Treatment Implications: 18. Does cannabis cause schizophrenia? Stan Zammit, Mary Cannon and Robin M. Murray; 19. Postmortem studies of the brain cannabinoid system in schizophrenia Suresh Sundram, Brian Dean and David Copolov; 20. The endogenous cannabinoid system in schizophrenia Paul Morrison; 21. The endocannabinoid system as a target for pharmacotherapy of schizophrenia Markus Leweke; Part VII. Cannabis and its Impact on Schizophrenia: 22. Acute effects of cannabis in established schizophrenia Cecile Henquet and Deepak Cyril D'Souza; 23. Cannabis and the long-term course of schizophrenia Don Liszen, Bart Peters and Lieuwe De Haan; 24. Motives that maintain cannabis use in schizophrenia Kim Meuser; 25. Treatment interventions for cannabis abuse in people with psychosis Wynne James and David Castle; Part VIII. Integration: 26. Cannabis and mental illness: an integration Deepak Cyril D'Souza, Robin M. Murray and David Castle; Index.