Individualized Medicine (eBook)

Preface1 Introduction Part I Definition and concept of Individualized Medicine 2  The meaning of “Individualized Medicine” – A terminological adjustment of a perplexing term3  Individualized Medicine within the GANI_MED project Part II Perspectives of socio-cultural and historical studies  4  Inventing traditions, raising expectations. Recent debates on “Personalized Medicine” 5  The “Epistemics” of “Personalized Medicine”. Rebranding pharmacogeneticsPart III Medical perspectives           6  Use of biomarkers for the prediction of treatment response: Immunoadsorption in dilated cardiomyopathy as a clinical example7  The role of pharmacogenomics in Individualized Medicine Part IV Concept-based ethical questions 8  On a philosophy of Individualized Medicine – Conceptual and ethical questions 9  The concept of disease in the era of prediction Part V Applied research ethics 10 Informed Consent in GANI_MED – A sectional design for clinical epidemiological studies within Individualized Medicine11 Ethics Meets IT: Aspects and elements of Computer-based informed consent processing 12 Handling incidental findings from imaging within IM related research Part VI Health economic assessment of Individualized Medicine13 Individualized Medicine: From potential to macro innovation 14 Assessing Individualized Medicine – the example of immunoadsorption 15 How individualized is medicine today? The case of heart failure in the G-DRG system 16 Conclusions and recommendationsIndex