Hereditary Peripheral Neuropathies

Dr. G. Kuhlenb?mer, PD Dr. F. St?bauer, Dr. P. Young, Prof. Dr. E.B. Ringelstein, Dep. of Neurology, University of Muenster, Germany

Architecture of the peripheral nerve.- Clinical evaluation and differential diagnosis.- Elecrodiagnostic evaluation of hereditary polyneuropaties.- Principles of pathology and nerve biopsy.- Overview of the classification and genetics of hereditary peripheral neuropathies and rare unclassified forms.- Charcot-Marie-Tooth disease type 1 (CMT1) and hereditary neuropathy with liability to pressure palsy (HNPP).- CMT2, dominant intermediate CMT and CMTX.- Distal hereditary motor neuropathies (dHMN).- Hereditary sensory and autonomic neuropathies (HSAN).- Hereditary neuralgic amyotrophy (HNA).- Molecular genetic diagnosis of hereditary neuropathies.- Genetic counseling.- Medical treatment of hereditary neuropathies.- Orthopedic aspects in diagnosis, clinical management and therapy of CMT patients.- Animal models of hereditary neuropathies.