Re-Engineering of the Damaged Brain and Spinal Cord (eBook)

Preface 6
Forewords 9
Contents 12
A. Evidence based neurorehabilitation 16
Evidence based medicine in neurological rehabilitation – a critical review 17
Quality management in traumatic brain injury ( TBI) Lessons from the prospective study in 6.800 patients after acute TBI in respect of neurorehabilitation 29
Posttraumatic epilepsy with special emphasis on prophylaxis and prevention 40
Swallowing therapy – a prospective study on patients with neurogenic dysphagia due to unilateral paresis of the vagal nerve, Avellis’ syndrome, Wallenberg’s syndrome, posterior fossa tumours and cerebellar hemorrhage 48
Impaired self-awareness after moderately severe to severe traumatic brain injury 51
Assessment of health-related quality of life in persons after traumatic brain injury – development of the Qolibri, a specific measure 55
B. Re-engineering of brain lesions 62
RNA editing: a molecular mechanism for the fine modulation of neuronal transmission 63
Inhibition of IkBa phosphorylation prevents glutamate-induced NF-kB activation and neuronal cell death 68
Reorganization of cerebral circuits in human brain lesion 73
Transcranial magnetic stimulation in neurorehabilitation 79
Is there impairment of a specific frontal lobe circuit in head injury? 83
Treating the aging brain: cortical reorganization and behavior 86
The localization of central pattern generators for swallowing in humans – a clinical- anatomical study on patients with unilateral paresis of the vagal nerve, Avellis’ syndrome, Wallenberg’s syndrome, posterior fossa tumours and cerebellar hemorrhage 92
Functional regeneration of the axotomized auditory nerve with combined neurotrophic and anti- inhibitory strategies 96
Electrically evoked hearing perception by functional neurostimulation of the central auditory system 99
Physiological recordings from electrodes implanted in the basal ganglia for deep brain stimulation in Parkinson’s disease. The relevance of fast subthalamic rhythms 102
DBS therapy for the vegetative state and minimally conscious state 105
Deep brain stimulation for idiopathic or secondary movement disorders 109
Extradural Motor Cortex Stimulation ( EMCS) for Parkinson’s disease. History and first results by the study group of the Italian neurosurgical society 116
Endocrine dysfunction following traumatic brain injury: mechanisms, pathophysiology and clinical correlations 123
Taylored implants for alloplastic cranioplasty – clinical and surgical considerations 128
Lessons from National and International TBI Societies and Funds like NBIRTT 131
C. Re-engineering of spinal cord lesions 134
Brachial plexus surgery ( Honorary lecture) 135
Results in brachial plexus palsy after biceps neuro-muscular neurotization associated with neuro- neural neurotization and teno- muscular transfer 139
Macrophages and dendritic cells treatment of spinal cord injury: from the bench to the clinic 144
Electrophysiological e¤ects of 4-aminopyridine on fictive locomotor activity of the rat spinal cord in vitro 148
Alternative, complementary, energy-based medicine for spinal cord injury 152
The e¤ect of penile vibratory stimulation on male fertility potential, spasticity and neurogenic detrusor overactivity in spinal cord lesioned individuals 156
Posttraumatic syringomyelia – a serious complication in tetra- and paraplegic patients 161
Functional neurorehabilitation in locked-in syndrome following C0– C1 decompression 164
Treatment options and results in cervical myelopathy 171
The treatment of the sacral pressure sores in patients with spinal lesions 177
D. Neurological-neurosurgical-neurobehavioral rehabilitation 182
Phenomenological aspects of consciousness – its disturbance in acute and chronic stages 183
Neuropsychological experiences in neurotraumatology 187
Team care in ICU – Psychotherapeutic aspects and taking care of family of patients with traumatic brain injury 191
Early clinical predictive factors during coma recovery 193
Predicting one year clinical outcome in traumatic brain injury ( TBI) at the beginning of rehabilitation 198
Severe brain injuries in children 200
The locked-in syndrome: a challenge for therapy 204
E. Addendum 208
WFNS committee for neurorehabilitation 209
Academia Multidisciplinaria Neurotraumatologica AMN* 212
NBIRTT, the National Brain Injury Research, Treatment and Training Foundation 216
Author index 217
Index of keywords 218