Anticoagulation Therapy (eBook)

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2018 | 1st ed. 2018
XXIX, 452 Seiten
Springer International Publishing (Verlag)
978-3-319-73709-6 (ISBN)

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This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.

Joe F. Lau MD, PhD, FACC, FASE, FSVM, RPVI

Associate Professor of Cardiology

Zucker School of Medicine at Hofstra/Northwell

Director of Vascular Medicine

Director of Non-Invasive Vascular Laboratory

Department of Cardiology

Northwell Health

New Hyde Park, NY


Geoffrey D. Barnes, MD, MSc

Associate Professor

Frankel Cardiovascular Center at the University of Michigan

Department of Internal Medicine

Division of Cardiovascular Medicine

Ann Arbor, MI


Michael B. Streiff, MD

Associate Professor of Medicine and Pathology

Division of Hematology

Department of Medicine

The Johns Hopkins University School of Medicine

Baltimore, MD 

Joe F. Lau MD, PhD, FACC, FASE, FSVM, RPVIAssociate Professor of CardiologyZucker School of Medicine at Hofstra/NorthwellDirector of Vascular MedicineDirector of Non-Invasive Vascular LaboratoryDepartment of CardiologyNorthwell HealthNew Hyde Park, NYGeoffrey D. Barnes, MD, MScAssistant ProfessorFrankel Cardiovascular Center at the University of MichiganDepartment of Internal MedicineDivision of Cardiovascular MedicineAnn Arbor, MIMichael B. Streiff, MDAssociate Professor of Medicine and PathologyDivision of HematologyDepartment of MedicineThe Johns Hopkins University School of MedicineBaltimore, MD 

1. Introduction; Joe F. Lau, Geoffrey D. Barnes, and Michael B. Streiff.- Part I. Anticoagulants.- 2. Warfarin; Gregory C. Hadlock, Allison E. Burnett, and Edith A. Nutescu.- 3. Unfractionated Heparin and Low-Molecular-Weight Heparin; Rhynn J. Malloy, Jessica Rimsans, Megan Rhoten, Katelyn Sylvester, and John Fanikosl.- 4. Parenteral Anticoagulants: Direct Thrombin Inhibitors and Pentasaccharides; Allison E. Burnett and Meghan L. Fletcher.- 5. Direct Oral Anticoagulants; Natalie S. Evans.- 6. Anticoagulation Reversal; Marcelo P. V. Gomes and Deborah Hornacek.- 7. Transitioning Between Anticoagulants; Marcelo P.V. Gomes and Maya Serhal.- Part II Clinical Applications of Anticoagulant Therapy.- 8. The Anticoagulation Clinic; Nathan P. Clark and Daniel M. Witt.- 9. Peri-Operative Management of Anticoagulants; Ibrahim M. Ali, Alexander Volodarskiy, and Joe F. Lau.- 10. Acute Coronary Syndromes; Nilay K. Patel and Sammy Elmariah.- 11. Antithrombotic Therapy for Patients with Atrial Fibrillation; Kyla M. Lara and Jonathan L. Halperin.- 12. Anticoagulant Strategies for Electrophysiology Procedures; Stuart J. Beldner and David L. Stern.- 13. Anticoagulation for Cardiac Prosthetic Devices: Prosthetic Heart Valves, Left Ventricular Assist Devices, and Septal Closure Devices; Matthew T. Crim, Supriya Shore, Suegene K. Lee, and Bryan J. Wells.- 14. Anticoagulation in Venous Thromboembolism; Geoffrey D. Barnes and Elizabeth T. Renner.- 15. Thrombophilic States; Adriana Guigova and Tony Philip.- 16. Thrombophilia Testing; Teresa L. Carman.- 17. Heparin-Induced Thrombocytopenia; Emily Downs, Svetlana Goldman, Surabhi Palkimas, Aditya M. Sharma.- 18. Anticoagulation Therapy in Pregnant Patients; Steven A. Savella, Jessica A. Kvasic, and Joe F. Lau.- 19. Anticoagulation in the Elderly; Ruchika Harisingani, Ibrahim M. Ali, Bhakti Shah, and Salonie Pereira.- 20. Anticoagulation in the Patient with Cancer; Simon Mantha, Dipti Gupta, Chadi Salmane, Mansour Khaddr, Gerald A. Soff, and Richard Steingart.

Erscheint lt. Verlag 16.4.2018
Zusatzinfo XXIX, 452 p. 42 illus., 30 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Innere Medizin
Schlagworte anticoagulation reversal • Anticoagulation Therapy • clinical applications of anticoagulant therapy • direct oral anticoagulants • heparin-induced thrombocytopenia • parenteral anticoagulants • pharmacologic properties of anticoagulants • Thrombophilia • unfractionated heparin • venous thromboembolism therapy • Warfarin
ISBN-10 3-319-73709-0 / 3319737090
ISBN-13 978-3-319-73709-6 / 9783319737096
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