Neurotoxicity of Metals (eBook)

Michael Aschner is the Gray E. B. Stahlman Professor of Pediatrics and Pharmacology at Vanderbilt University School of Medicine as well as a Senior Investigator at the Kennedy Center for Research on Human Development. Dr Aschner’s research group has a particular interest in the neurobiology and physiology of astrocytes and the signaling mechanisms associated with central nervous system injury. Dr Aschner’s laboratory studies metal uptake and distribution in the brain, investigating the mechanisms of transport of methylmercury and manganese across the capillaries of the blood–brain barrier. His research utilizes various experimental models (C. elegans, tissue cultures and rodents) to understand the acute toxicity of manganese deposition in the brains of human neonates.​Lucio G. Costa is Professor of Environmental and Occupational Health Sciences at the School of Public Health at the University of Washington. Dr. Costa is a renowned neurotoxicologist whose research interests are focused on understanding the role of neurotoxic substances in neurodevelopmental disorders and other neurological, neuropsychiatric and neurodegenerative diseases. Dr Costa’s research laboratory makes use of a variety of in vivo and in vitro cell culture systems, transgenic animal models and imaging techniques to study the cellular, biochemical and molecular mechanisms of neurotoxicity.

Aschner                                   Manganese and PD Costa                                       Metals and paraoxonases Fox                                           Pb and visual system Guilarte                                   Pb (Mn) and neurodegeneration or Schizophrenia Cory-Slechta                 Pb and stress interactions in developmental neurotoxicity Tjalkens                     Metals induced neuroinflammation Brazilians                   MeHg and neurodegeneration Grandjean                    MeHg developmental neurotoxicity Lucchini                     Mn epi Sanders (Mount Sinai)        Cadmium neurotoxicity Bondy                   ;     Aluminum neurotoxicity Syed Ali/Saber               Metal nanoparticles neurotoxicity     Tony White                   Metals and AD Aizenman                     Zinc and ADConnor        Fe neurotoxicity