Contemporary Oral Oncology (eBook)

This is the first of four volumes that together offer an authoritative, in-depth reference guide covering all aspects of the management of oral cancer from a multidisciplinary perspective and on the basis of a strong scientific foundation. This volume, on tumor biology, epidemiology, etiology, emerging role of cancer stem cells and prevention of oral cancer, opens by discussing oral carcinogenesis in general and the role of particular carcinogens and human papillomavirus. Global epidemiology and changes in disease prevalence are then addressed. Up-to-date information is provided on emerging cancer biomarkers, and the biologic basis of personalized therapy is explained. Histopathological features of malignant and premalignant neoplasms and their relevance to management are described. Further chapters focus on the current status of chemoprevention, the management of oral submucous fibrosis, and the value of various diagnostic adjuncts. The volume concludes by critically evaluating the efficacy of oral screening methods.

Moni Abraham Kuriakose, BSc, BDS, MB ChB, MD, FDSRCS, FFDRCS, FRCS Ed, FRCS (Maxillofacial Surgery), is Director of the Translational Research Program and Attending Surgeon in the Department of Head and Neck/Plastic and Reconstructive Surgery at the Roswell Park Cancer Institute, Buffalo, New York, and Professor of Surgery, Director of the Department of Surgical Oncology, and Chief of the Division of Head and Neck Oncology at the Mazumdar-Shaw Cancer Center, Narayana Health City, Bangalore, India. In addition, he is Adjunct Associate Professor in the Departments of Oral and Maxillofacial Surgery and Otolaryngology at New York University. Dr. Kuriakose has received numerous honors and awards and has held many national and international leadership positions, including as Chairman of the Oral Cancer Special Interest Group, International Association of Oral and Maxillofacial Surgeons (2008-2012),  Secretary General of the International Academy of Oral Oncology (2013-2015) and President of Indian Head and Neck Oncology Society (2015-2017). He is a member of the editorial boards for Oral Oncology and the Journal of Maxillofacial and Oral Surgery, and a reviewer for a number of other leading journals. Dr. Kuriakose's research group focuses on two key challenges: down-staging and prevention of oral cancer; and reversing chemotherapy resistance. He has been the principal investigator on many research projects and is the author of over 150 peer-reviewed publications.