Handbook of Ion Chromatography (eBook)

Joachim Weiss studied chemistry at the Technical University of Berlin (Germany), where he also received his PhD degree in Analytical Chemistry. In 2002, he did his habilitation in Analytical Chemistry at the Leopold-Franzens University in Innsbruck (Austria), where he is also teaching liquid chromatography. Since 1982, Dr. Weiss has worked at Dionex (now being part of Thermo Fisher Scientific), where he currently holds the position of Technical Director for Dionex Products within the Chromatography and Mass Spectrometry Division (CMD) of Thermo Fisher Scientific, located in Dreieich (Germany).

Foreword
Preface to the Fourth Edition

1 INTRODUCTION
1.1 Historical Perspective
1.2 Types of Ion Chromatography
1.3 The Ion Chromatographic System
1.4 Advantages of Ion Chromatography
1.5 Selection of Separation and Detection Systems

2 THEORY OF CHROMATOGRAPHY
2.1 Chromatographic Terms
2.2 Parameters for Assessing the Quality of a Separation
2.3 Column Efficiency
2.4 The Concept of Theoretical Plates (van Deemter Theory)
2.5 Van Deemter Curves in Ion Chromatography

3 ANION-EXCHANGE CHROMATOGRAPHY (HPIC)
3.1 General Remarks
3.2 The Ion-Exchange Process
3.3 Thermodynamic Aspects
3.4 Stationary Phases
3.5 Eluents for Anion-Exchange Chromatography
3.6 Suppressor Systems in Anion-Exchange Chromatography
3.7 Anion-Exchange Chromatography of Inorganic Anions
3.8 Anion-Exchange Chromatography of Organic Anions
3.9 Gradient Elution Techniques in Anion-Exchange Chromatography of Inorganic and Organic Anions
3.10 Carbohydrates
3.11 Amino Acids
3.12 Anion-Exchange Chromatography of Proteins
3.13 Nucleic Acids

4 CATION-EXCHANGE CHROMATOGRAPHY (HPIC)
4.1 Stationary Phases
4.2 Eluents in Cation-Exchange Chromatography
4.3 Suppressor Systems in Cation-Exchange Chromatography
4.4 Cation-Exchange Chromatography of Alkali Metals, Alkaline-Earth Metals, and Amines
4.5 Transition Metal Analysis
4.6 Analysis of Polyamines
4.7 Gradient Techniques in Cation-Exchange Chromatography of Inorganic and Organic Cations
4.8 Cation-Exchange Chromatography of Proteins

5 ION-EXCLUSION CHROMATOGRAPHY (HPICE)
5.1 The Ion-Exclusion Process
5.2 Stationary Phases
5.3 Eluents for Ion-Exclusion Chromatography
5.4 Suppressor Systems in Ion-Exclusion Chromatography
5.5 Analysis of Inorganic Acids
5.6 Analysis of Organic Acids
5.7 HPICE/HPIC-Coupling
5.8 Analysis of Alcohols and Aldehydes
5.9 Amino Acids Analysis
5.10 Size-Exclusion Chromatography of Proteins

6 ION-PAIR CHROMATOGRAPHY (MPIC)
6.1 Survey of Existing Retention Models
6.2 Suppressor Systems in Ion-Pair Chromatography
6.3 Experimental Parameters that Affect Retention
6.4 Analysis of Surface-Inactive Ions
6.5 Analysis of Surface-Active Ions
6.6 Applications of the Ion-Suppression Technique
6.7 Applications of Ion Chromatography on Mixed-Mode Stationary Phases

7 HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC)
7.1 Separation Mechanism in Hydrophilic Interaction Liquid Chromatography
7.2 Stationary Phases for HILIC
7.3 Factors Affecting Retention in HILIC
7.4 Applications

8 DETECTION METHODS IN ION CHROMATOGRAPHY
8.1 Electrochemical Detection Methods
8.2 Spectrometric Detection Methods
8.3 Aerosol-Based Detection Methods
8.4 Other Detection Methods
8.5 Hyphenated Techniques

9 QUANTITATIVE ANALYSIS
9.1 General
9.2 Analytical Chemical Information Parameters
9.3 Determination of Peak Areas
9.4 Statistical Quantities
9.5 Calibration of an Analytical Method (Basic Calibration)
9.6 Detection Criteria, Limit of Detection, Limit of Determination
9.7 The System of Quality Control Cards

10 APPLICATIONS
10.1 Ion Chromatography in Environmental Analysis
10.2 Ion Chromatography in Power Plant Chemistry
10.3 Ion Chromatography in the Semiconductor Industry
10.4 Ion Chromatography in the Electroplating Industry
10.5 Ion Chromatography in the Detergent and Household Product Industry
10.6 Ion Chromatography in the Food and Beverage Industry
10.7 Ion Chromatography in the Pharmaceutical Industry
10.8 Ion Chromatography in Clinical Chemistry
10.9 Oligosaccharide Analysis of Membrane-Coupled Glycoproteins
10.10 Chemical and Petrochemical Applications
10.11 Other Applications
10.12 Sample Preparation and Matrix Problems
10.13 Concluding Remarks

From reviews of previous editions:
"This book is an excellent reference for someone starting out or practicing IC"
Journal of the American Chemical Society
"All aspects of ion chromatography, including ion-exclusion chromatography and ion-pair chromatography, are covered. The book is lavishly illustrated with figures. This is a book I would recommend highly to practitioners of ion chromatography at all levels."
Analytical Chemistry
"The text is written in an easily readable style, the topics are covered in a systematic and logical manner and the book is well illustrated with numerous chromatograms and figures. I am sure that it will be a success and I recommend it strongly."
Journal of Chromatography A
"This book will prove to be a valuable resource for seasoned ion chromatographers and newcomers to the technique alike"
Analytica Chimica Acta


"This book is an important, comprehensive reference for anyone in the chemical sciences seeking to use ion chromatography in their research."
Journal of the American Chemical Society

"...covers every conceivable topic related to the growing and increasingly important topic of ion chromatography."
CHOICE

"...the definitive source book on ion chromatography, written by one of the major researchers in the field who writes on the subject with lucid and erudite elegance."
Electric Review