Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer -

Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer (eBook)

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2015 | 2015
XIII, 168 Seiten
Springer New York (Verlag)
978-1-4939-2035-8 (ISBN)
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This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing 'true' DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer.

Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.



Lisa A. Newman, MD, MPH, FACS
Professor of Surgery, Director, Breast Care Center, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USA

Jessica M. Bensenhaver, MD
Assistant Professor of Surgery, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USA


This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing "e;true"e; DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer.Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

Lisa A. Newman, MD, MPH, FACSProfessor of Surgery, Director, Breast Care Center, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USAJessica M. Bensenhaver, MDAssistant Professor of Surgery, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USA

1. Epidemiology of Ductal Carcinoma In SituPrathima Kanumuri and Anees Chagpar2. Role of Screening Mammography in Early Detection/Outcome from Breast CancerRenee W. Pinsky and Mark A. Helvie3. Imaging DCIS: Digital/Film Screening Mammography, Tomosynthesis, MRI, UltrasonographyAnnette Ingram Joe and Stephanie K. Patterson4. Pathology of Ductal Carcinoma In Situ: Features and Diagnostic ChallengesJulie M. Jorns and Celina G. Kleer5. Molecular Markers in DCISChelsea Horwood and Theresa L. Schwartz6. History of Ductal Carcinoma In Situ Management Based Upon Data from Prospective, Randomized Clinical TrialsLisa A. Newman and Jessica M. Bensenhaver7. Extent and Role of Margin Control for DCIS Managed by Breast-Conserving SurgeryMelissa Pilewskie and Monica Morrow8. Ductal Carcinoma In Situ Treated With Breast Conserving Surgery AloneJessica M. Bensenhaver9. DCIS Managed with BCS: Whole-Breast XRT vs. Partial Breast XRTChirag Shah and Frank A. Vicini10. Anti-HER2/neu Therapy in DCISAmelia Tower, Ruta D. Rao, Kalliopi P. Siziopikou, Melody A. Cobleigh and Thomas B. Julian11. Role of Genetic Profiling and Recurrence Scores in Treatment Planning for DCISJulie A. Margenthaler and Amy E. Cyr12. DCIS and Sentinel Lymph Node BiopsyAlfred J. Colfry, 3rd, Alastair M. Thompson and Henry Mark Kuerer13. Role of Postmastectomy Radiation for DCISCorey W. Speers and Reshma Jagsi14. Monitoring and Surveillance Following DCIS Treatment Jennifer Zakhireh and E. Shelley Hwang15. DCIS and Hereditary Susceptibility for Breast CancerPatrick Pilie, Kara Milliron and Sofia D. Merajver16. Introduction, Evolution and Application of the Van Nuys Prognostic Index in DCISAeisha K. S. Rivers17. Disparities in DCIS Detection and Outcomes Related to Race/EthnicityErin A. Strong, Azadeh Stark and Lisa A. Newman

Erscheint lt. Verlag 4.2.2015
Zusatzinfo XIII, 168 p. 35 illus., 32 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Medizin / Pharmazie Medizinische Fachgebiete Gynäkologie / Geburtshilfe
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Schlagworte Breast Tomosynthesis • DCIS • SERM therapy • surgical oncology • ultrasonography
ISBN-10 1-4939-2035-9 / 1493920359
ISBN-13 978-1-4939-2035-8 / 9781493920358
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