Nicotinic Receptors (eBook)
XVII, 461 Seiten
Springer New York (Verlag)
978-1-4939-1167-7 (ISBN)
A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system and discussion of their implications in learning and memory, addiction and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.
A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system and discussion of their implications in learning and memory, addiction and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.
Ch. 1: On the Discovery of the Nicotinic Acetylcholine Receptor Channel Richard Martindale, Robin A.J. Lester, Ph.D., Ch. 2: Molecular Structure and GatingSteen E. Pedersen, Ph.DCh. 3: Molecular Underpinnings of Neuronal Nicotinic Acetylcholine Receptor ExpressionMichael D. Scofield, Ph.D., Paul D. Gardner, Ph.D.,Ch. 4: Presynaptic Nicotinic Receptors: Subtypes and FunctionMichael J. Marks, B.S., M.S., Ph.D., Sharon R. Grady, Ph.D. Tristan D. McClure-Begley, Ph.D. Heidi C. O’Neill, Ph.D., Cristian A. Zambrano, Ph.D. Ch. 5: Functional Distribution and Regulation of Neuronal Nicotinic Acetylcholine Receptors in the Mammalian BrainJerrel L. Yakel, Ph.D.Ch. 6: Nicotinic Signaling in DevelopmentCatarina C. Fernandes, Ph.D. Adrian F. Lozada, Ph.D. Darwin K. Berg, Ph.D.Ch. 7: Presynaptic Nicotinic Acetylcholine Receptors & The Modulation Of Circuit ExcitabilityChongbo Zhong, M.D. Ph.D., Gretchen Y. Lopez-Hernandez, Ph.D., David A. Talmage, Ph.D., Lorna W. Role, Ph.D.Ch. 8: Autonomic Nervous System TransmissionPeter B. Sargent, Ph.D.Ch. 9: Nicotinic Receptors in the Spinal CordBoris Lamotte d’Incamps, Philippe AscherCh. 10: Slow Synaptic Transmission in the Central Nervous SystemA. Rory McQuiston, Ph.DCh. 11: The Effects of Nicotine on Learning and MemoryThomas J. Gould, Ph.DCh. 12: Nicotinic Receptors as Targets for Novel Analgesics and Anti-Inflammatory DrugsM. Imad Damaj, Ph.D., Kelen Freitas, Deniz Bagdas, Ph.D., Pamela Flood, M.D.Ch. 13: Nicotinic Acetylcholine Receptors and the Roles of the Alpha7 SubunitMichael Paolini, M.D., Mariella De Biasi, Ph.D., John A. Dani, Ph.D.Ch. 14: Role of Central Serotonin Receptors in Nicotine Addiction Giuseppe Di Giovanni , Ph.D., Massimo Pierucci, B.Sc. Stephanie Chambers, Lucy Partridge, Philippe De Deurwaerdère, Ph.D., Ch. 15: Neuronal Nicotinic Acetylcholine Receptors in Reward and AddictionAndrew R. Tapper, Ph.D., Linzy M. Hendrickson, Ph.D.Ch. 16: Genetic Contributions of the α5 Nicotinic Receptor Subunit to Smoking BehaviorLaura J. Bierut, M.D., Jerry A. Stitzel, Ph.D. Ch. 17: Smoking‐Related Genes and Functional ConsequencesInes Ibañez-Tallon, Ph.D., Jessica L. Ables, M.D., Ph.D.Ch. 18: Nicotinic Acetylcholine Receptors Along the Habenulo-Interpeduncular Pathway: Roles in Nicotine Withdrawal and Other Aversive Aspects Dang Q. Dao, B.S., Ramiro Salas, Ph.D., Mariella De Biasi, Ph.D.Ch. 19: Nicotinic Acetylcholine Receptors in Alzheimer’s and Parkinson’s DiseaseKelly T Dineley, Ph.D.Ch. 20: Nicotinic Receptors and Mental IllnessSherry Leonard, Ph.D.Ch. 21: Current & Future Trends in Drug Discovery and Development Related to Nicotinic ReceptorsStephen P Arneric, Ph.D., Emanuele Sher, M.D., Ph.D.
| Erscheint lt. Verlag | 11.11.2014 |
|---|---|
| Reihe/Serie | The Receptors |
| Zusatzinfo | XVII, 461 p. 42 illus., 31 illus. in color. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
| Medizin / Pharmazie ► Studium | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Schlagworte | Behavior • Disease • molecular structure • Subtypes • synaptic transmission |
| ISBN-10 | 1-4939-1167-8 / 1493911678 |
| ISBN-13 | 978-1-4939-1167-7 / 9781493911677 |
| Haben Sie eine Frage zum Produkt? |
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