Vienna1865: Dr Ignaz Semmelweis has been hounded into a lunatic asylum, ridiculed for his claim that doctors' unwashed hands are the root cause of childbed fever. The deaths of thousands of mothers are on his conscience and his dreams are filled with blood. 2153: humans are birthed and raised in breeding centres, nurtured by strangers and deprived of familial love. Miraculously, a woman conceives, and Prisoner 730004 stands trial for concealing it. London in 2009: Michael Stone's novel about Semmelweis has been published, after years of rejection. But while Michael absorbs his disconcerting success, his estranged mother is dying and asks to see him again. As Michael vacillates, Brigid Hayes, exhausted and uncertain whether she can endure the trials ahead, begins the labour of her second child. A beautifully constructed and immensely powerful work about motherhood that is also a story of rebellion, isolation and the damage done by rigid ideologies.

Joanna Kavenna grew up in various parts of Britain, and has also lived in the USA, France, Germany, Scandinavia and the Baltic States. Her first book The Ice Museum was about travelling in the North. Her second book, a novel called Inglorious, won the Orange Prize for New Writing. Kavenna's writing has appeared in the London Review of Books, the Guardian and Observer, the Times Literary Supplement, the International Herald Tribune, the Spectator and the Telegraph, among other publications. She has held writing fellowships at St Antony's College, Oxford and St John's College, Cambridge. She currently lives in the Duddon Valley, Cumbria., Joanna Kavenna is the author of several works of fiction and non-fiction including The Ice Museum, Inglorious, The Birth of Love and A Field Guide to Reality. Her short stories and essays have appeared in the New Yorker, the LRB, the New Scientist, the Guardian and the New York Times. In 2008 she won the Orange Prize for New Writing, and in 2013 she was named one of Granta's Best Young British Novelists.

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Vienna1865: Dr Ignaz Semmelweis has been hounded into a lunatic asylum, ridiculed for his claim that doctors' unwashed hands are the root cause of childbed fever. The deaths of thousands of mothers are on his conscience and his dreams are filled with blood. 2153: humans are birthed and raised in breeding centres, nurtured by strangers and deprived of familial love. Miraculously, a woman conceives, and Prisoner 730004 stands trial for concealing it. London in 2009: Michael Stone's novel about Semmelweis has been published, after years of rejection. But while Michael absorbs his disconcerting success, his estranged mother is dying and asks to see him again. As Michael vacillates, Brigid Hayes, exhausted and uncertain whether she can endure the trials ahead, begins the labour of her second child. A beautifully constructed and immensely powerful work about motherhood that is also a story of rebellion, isolation and the damage done by rigid ideologies.