Animal Tumors of the Female Reproductive Tract

Spontaneous and Experimental

E. Cotchin, J. Marchant (Autoren)

Buch | Softcover

70 Seiten

1978 | Softcover reprint of the original 1st ed. 1977
Springer-Verlag New York Inc.
978-1-4684-6261-6 (ISBN)

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The chapters which comprise this book were prepared as part of a medical text, Pathology of the Female Genital Tract, which is intended for the obstetrician, gynecologist, and medical pathologist. In that context, we were con cerned to bring out the importance of the study of tumors of the female reproductive tract of animals, both as show ing the variety of spontaneous neoplasms that might affect the tract and as providing tumors capable of experimental reproduction. These chapters are published separately, since they contain information which may appeal to a range of readers who might not necessarily wish to acquire the full medical text-for example, to veterinary and comparative pathologists, cancer research workers, research workers in gynecology, experimental pathologists and endocrinologists, and possibly to others using animals in experimental and pharmaceutical studies. The survey of spontaneous tumors of the female repro ductive tract is largely concerned with tumors of the ovaries and uterus of domesticated animals, but attention is also given to laboratory animals, wild animals, and animals in zoos. The spontaneous tumors are well worth studying, not only because of their obvious clinical impor tance to veterinarians, but also because they might provide a stimulus for epidemiologic, etiologic, biologic, and ther apeutic investigations that may elucidate some of the problems related to their counterparts in humans.

1 Animal Models for Tumors of the Ovary and Uterus.- General Introduction.- Animal Models for Tumors of the Ovary.- The Ovary as a Tumor Model.- Spontaneous Ovarian Tumors in Laboratory Animals.- Methods of Inducing Ovarian Tumors in Mice.- Direct Methods.- X-Irradiation.- Chemical Carcinogens.- Transplantation.- Ovarian Vasoligation.- Thymectomy.- Genetic Deletion.- Indirect Methods.- Intrasplenic Ovary Grafting to a Castrate.- Parabiosis with a Castrate.- Transplantation of a Gonadotropic Pituitary Tumor.- Noncyclic Exposure to Bright Illumination.- Chronic Exposure to Other Hormones.- Progestational agents.- Estrogens.- Androgens.- Thyroid hormone.- Influence of Hormones on Ovarian Tumor Induction by Other Agents.- Pathology and Histogenesis of Ovarian Tumors.- Tubular Adenoma.- Granulosa-Theca Cell Tumors.- Luteomas.- Cystadenomas.- Teratomas.- Metastatic Tumors to the Ovary.- Assessment of the Present Animal Tumor Models of Ovarian Cancer.- Animal Models for Tumors of the Uterine Fundus and Placenta.- The Uterus as a Tumor Model.- Spontaneous Uterine Tumors in Laboratory Animals.- Methods of Inducing Tumors of the Uterine Fundus in Laboratory Animals.- Hormone imbalance.- Estrogens.- Estrogens Plus Androgens.- Progesterones.- Testicular Grafts.- Ovarian Fragmentation.- Pituitary Growth Hormone.- Carcinogens.- Chemicals.- 3-Methylcholanthrene (MC).- 7,12-Dimethylbenz[a]Anthracene (DMBA).- 2-Fluorenylacetamide (FAA).- N,N-Fluorenyldiacetamide.- Vinyl Copolymer.- Intrauterine Devices.- X-Irradiation.- Viruses.- Methods of Inducing Placental Tumors in Laboratory Animals.- Chemical Carcinogens after Fetectomy.- Virus after Fetectomy.- Destruction of the Hypothalamic Nucleus.- Animal Models for Tumors of the Uterine Cervix, Vagina, and Vulva.- Methods of Inducing Tumors in Laboratory Animals.- Hormones.- Estrogens.- Testosterone.- Chemical Carcinogens.- Dibenz [a * h]anthracene (DBA) and Theelin.- Benzo [a]pyrene (BP).- 3-Methylcholanthrene (MC).- Dimethylbenz[a]anthracene (DMBA).- Carbowax 1000 (Polyethylene Glycol).- N,N1-Dimethyl-N-Nitrosourea.- Virus.- Herpesvirus Type 2 (HSV-2).- Assessment of the Animal Tumor Models for Cancer of the Uterus.- Laboratory Animals as Hosts for Human Tumors.- References.- 2 Spontaneous Tumors of the Uterus and Ovaries in Animals.- General Introduction.- Spontaneous Tumors of the Uterus.- Domesticated Animals: General Survey.- Mare (Equus caballus).- Ewe (Ovis aries).- Goat (Capra hircus).- Sow (Sus scrofa).- Dog (Canis familiaris).- Cat (Felis catus).- Fowl (Gallus domesticus).- Laboratory Animals: General Survey.- Primates.- Mouse.- Rat.- Guinea Pig.- Hamster.- Gerbil.- Wild Animals, Animals in Zoos, and Birds: General Survey.- Domesticated Animals: Detailed Account.- Cow (Bos taurus).- Laboratory Animal: Detailed Account.- Rabbit (Oryctolagus cuniculus).- Spontaneous Tumors of the Ovary.- Domesticated Animals with Infrequently Reported Tumors.- Ewe.- Goat.- Sow.- Buffalo.- Laboratory Animals.- Primates.- Mouse.- Rat.- Guinea Pig.- Hamster.- Gerbil.- Ferret.- Mastomys.- Wild Animals, Animals in Zoos, and Birds.- Insect Study.- Domesticated Animals with Most Frequently Reported Tumors.- Mare.- Cow.- Cat.- Fowl.- Dog.- Types of Canine Ovarian Tumors.- Group 1: Papilloma and Adenoma.- Carcinoma.- Group 2: Granulosa Cell Tumor (GCT).- Group 3: Seminoma (Dysgerminoma).- Teratomas.- General Discussion of Canine Ovarian Tumors.- Summary.- References.

Erscheinungsdatum	20.12.2018
Zusatzinfo	31 Illustrations, black and white; IX, 70 p. 31 illus.
Verlagsort	New York, NY
Sprache	englisch
Maße	216 x 280 mm
Themenwelt	Veterinärmedizin
Schlagworte	Female reproductive tract • Genitalkrebs • Tierheilkunde • Tumor • Tumors
ISBN-10	1-4684-6261-X / 146846261X
ISBN-13	978-1-4684-6261-6 / 9781468462616
Zustand	Neuware