Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing (eBook)

Dr. Ganapathy Subramanian is a biotechnology consultant with over 30 years of experience in industry and academia, encompassing the application and development of processing, purification methodologies, and chromatographic systems for large scale use in environmental science, food science, perfumery, cosmetics, and pharmaceuticals. He has also taught extensively in the area of food and medical technology. A chemistry graduate from Madras, India, Dr. Subramanian was awarded his doctorate from the University of Glasgow for work on natural products. His main research interests lie in the utilization of natural material separation processes and bioconversions. Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 15 years, he has been organizing conferences promoting the integration and sharing of knowledge between academia and industry.

Part I - Continuous Biomanufacturing
1. Strategies for Continuous Processing in Microbial Systems
2.Control of Continuous Manufacturing Processes for Production of Monoclonal Antibodies
3.Artifical Intelligence and the Control of Continuous Manufacturing

Part II - Intensified Biomanufacturing
4. Bioprocess Intensification: Technologies and Goals
5. Process Intensification Based on Disposable Solutions as First Step toward Continuous Processing
6. Single-Use Continuous Manufacturing and Process Intensification for Production of Affordable Biological Drugs

Part III - Digital Biomanufacturing
7. Process Intensification and Industry 4.0: Mutually Enabling Trends
8. Consistent Value Creation from Bioprocess Data with Customized Algorithms: Opportunities Beyond Multivariate Anaysis
9. Digital Twins for Continuous Biologics Manufacturing
10. Regulatory and Quality Considerations of Continuous Bioprocessing