Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes

Dr Lucas Freitas de Freitas is a Biomedical Professional, graduated at State University of Londrina, Brazil (2009), with a PhD degree in bioengineering from University of São Paulo, Brazil (2016). Part of his PhD research was performed under supervision of Professor Dr Michael Hamblin from Wellman Center for Photomedicine, Harvard Medical School (2014–15). Dr Lucas has publications in the biomedical field, especially on light interaction with microorganisms and with the human body, cancer therapies and diagnostics, and oxidative stress. Michael R Hamblin PhD is a Principal Investigator at the Wellman Center for Photomedicine, Massachusetts General Hospital, an Associate Professor of Dermatology, Harvard Medical School and affiliated faculty at Harvard-MIT Division of Health Science and Technology. He directs a laboratory of around a dozen scientists who work in photodynamic therapy and low-level light therapy. He has published 320 peer-reviewed articles, is Associate Editor for 10 journals and serves on NIH Study-Sections. He has edited 11 proceedings volumes together with eight other major textbooks on PDT and photomedicine. In 2011 Dr Hamblin was honored by election as a Fellow of SPIE.

Introduction
Fullerenes
Resonant energy transfer
Photo-induced charge-transfer
Fullerenes as photosynthesizers
Chemical modifications
Examples of the synthesis of monocationic and polycationic
Photodynamic therapy
Photosensitizer formulations for fullerene-mediated PDT
In vitro anti-cancer PDT with fullerenes
In vivo PDT for cancer
Antibiotic resistance and viral infections
general aspects of photodynamic inactivation of bacteria
In vitro antimicrobial PDT with fullerenes
In vivo antimicrobial PDT with fullerenes
Conclusions