Natural Products Chemistry of Botanical Medicines from Cameroonian Plants

Dr. Xavier Siwe-Noundou is a scholar and scientist based at Rhodes University in Grahamstown / Makhanda, South Africa. He has been a Gordon and Betty Moore Foundation (GBMF) Fellow (2017-2019), Oregon State University in USA (2017), University of California San Diego in USA (2019); an EU FP7 Marie Curie Fellow (2015–2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr. Siwe-Noundou works on medicinal chemistry focusing on chemistry, pharmacognosy, and nanotechnology. His main investigations include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from South Africa cost line). All the bioactive metabolites isolated are screened as potential antimicrobial, antiparasitic and antiproliferative candidates. He is an author of more than fifty scientific publications in his field of expertise.

Contents

Book Series: Natural Products Chemistry of Global Plants.....................................vii

Introduction – Cameroon...........................................................................................ix

Editor........................................................................................................................xi

Contributors............................................................................................................ xiii

Chapter 1 The Genus Olax: Traditional Uses, Phytochemistry

and Biological Activities.......................................................................1

Bienvenu Tsakem, Beaudelaire Kemvoufo Ponou,

Billy Tchegnitegni Toussie, Romuald Fouedjou Tematio,

Xavier Siwe-Noundou, Rui W.M. Krause,

Rémy Bertrand Teponno, and Léon Azefack Tapondjou

Chapter 2 Chemistry and Biological Activities of Cameroonian

Hypericum Species..............................................................................23

Gabin Thierry M. Bitchagno, Vaderament-A

Nchiozem-Ngnitedem, Sylvain Valere Sob, and Serge Alain Fobofou

Chapter 3 Biologically Active Saponins from Some Cameroonian

Medicinal Plants.................................................................................. 37

Léon Azefack Tapondjou, Rémy Bertrand Teponno,

Beaudelaire Kemvoufo Ponou, Romuald Tematio Fouedjou,

and Luciano Barboni

Chapter 4 Antioxidant and Immunomodulatory Activities of Cameroonian

Medicinal Plants..................................................................................83

Matthias Onyebuchi Agbo, Patience O. Osadebe,

Xavier Siwe-Noundou, and Rui W.M. Krause

Chapter 5 Chemometric Evaluation of Phytochemical Principles in

Cameroonian Plants............................................................................99

Ezealisiji Kenneth Maduabuchi

Chapter 6 Medicinal Plants from Cameroon for Obstetric

and Gynecological Uses.................................................................... 123

Bazil Ekuh Ewane, Benjamin C. Ozumba, Patience O. Osadebe,

Philip F. Uzor, and Xavier Siwe-Noundou

vi Contents

Chapter 7 Ondongdong si (Acmella caulirhiza Delile), a Medicinal Plant

from Cameroon................................................................................. 141

Tanyi M. Kima and Eleonora D. Goosen

Chapter 8 Cameroonian Allanblackia Species.................................................. 183

Jean Emmanuel Mbosso Teinkela

Index ...................................................................................................................... 201