iPSCs in Tissue Engineering

Dr. Alexander Birbrair received his bachelor’s biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA), and in 2021, he was elected affiliate member of The World Academy of Sciences (TWAS). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.

1. Pluripotent Stem Cell-derived Brain-Region-Specific Organoids
2. The Construction Of 3D Cognitive Networks Through Precise Spatiotemporal Specification
3. Induced Pluripotent Stem Cells for Vascular Tissue Engineering
4. Induced Pluripotent Stem-Cell-Derived Corneal Grafts and Organoids
5. Induced Pluripotent Stem-Cell-Derived Salivary Glands
6. Induced Pluripotent Stem Cells for Trachea Engineering
7. Looking Back, Moving Forward: The Renaissance, Applications and Vascularization Strategies of Human Induced Pluripotent Stem Cell-Derived Lung Organoids
8. Skeletal Muscle Using Human Induced Pluripotent Stem Cells for In Vitro Disease Modeling
9. iPSC Bioprinting for Musculoskeletal Tissue
10. iPSC-Derived 3D Human Fatty Liver Models
11. iPSC-Derived Intestinal Organoids and Current 3D Intestinal Scaffolds
12. Models of Kidney Glomerulus Derived from Human-Induced Pluripotent Stem Cells
13. Ureteric Bud Structures Generated from Human iPSCs