Biointegration of Medical Implant Materials

Dr. Chandra P. Sharma is a former Adjunct Professor, Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal University, and Hon. Emeritus Professor, College of Biomedical Engineering and Applied Sciences, Purbanchal University, Kathmandu, Nepal. Dr. Sharma is a Solid-State Physicist from IIT Delhi and received his training in biomaterials area in the University of Utah with Prof. D.J. Lyman as a graduate student and in the University of Liverpool, England, with Prof. D.F. Williams as a Post-Doctoral Research Associate. Dr. Sharma has been awarded FBSE (Fellow Biomaterials Science and Engineering) by the International Union of Societies for Biomaterials Science and Engineering (IUS-BSE) in 2008 and FBAO (Fellow Biomaterials and Artificial Organs) by the Society for Biomaterials and Artificial Organs (India) (SBAOI) in 2011 and [17020_LE1] shares Whitaker and National Science Foundation Award—International Society for Artificial Organs (ISAO) USA, invited member ACS (2015–2018). [17020_LE1]Please check the phrase “and shares Whitaker and National…” for clarity and amend if necessary.

1. Biointegration: an introduction

Part One Soft tissue biointegration 2. Interface biology of stem cell-driven tissue engineering: concepts, concerns, and approaches 3. Replacement materials for facial reconstruction at the soft tissue–bone interface 4. Tissue engineering for small-diameter vascular grafts 5. Clinical applications of mesenchymal stem cells

Part Two Tissue regeneration 6. Cardiac Regeneration 7. Tissue-based products 8. Tendon and tissue regeneration 9. Integration of dental implants: molecular interplay at tissue-material interface 10. Biointegration of bone graft substiutes from osteointegration to osteotranduction 11. Stem cell-based therapeutic approaches toward corneal regeneration

Part Three Drug delivery 12. Biocompatibility of materials and its relevance to drug delivery and tissue engineering 13. Inorganic nanoparticles for targeted drug delivery 14. Applications of alginate biopolymer in drug delivery

Part Four Design considerations 15. Failure mechanisms of medical implants and their effects on outcomes 16. Biointegration of three-dimensional-printed biomaterials and biomedical devices