Fluorine Magnetic Resonance Imaging

Ulrich Flögel is professor of experimental cardiovascular imaging at the Heinrich Heine University of Düsseldorf, Germany. His research focuses on the interplay of function, energetics, metabolism, and inflammation and its role in the development of cardiovascular diseases using innovative multinuclear MRI/MRS techniques. Eric Ahrens is professor of radiology and director of Stem Cell Molecular Imaging at the University of California, San Diego. His research focuses on adapting MRI to visualize cellular and molecular events in vivo. His lab is developing novel materials and methods for MRI-based cell tracking that are used for monitoring cell therapies and cellular immunological processes.

Technical Issues. Pulse Sequence Considerations and Schemes. Advanced Detection Techniques and Hardware: Simultaneous 1H/19F. Hyperpolarization for Signal Enhancement (Naumann/Bernading; Magdeburg, Germany) 19F Imaging Agents. Active Targeting of Perfluorocarbon Nanoemulsions. Responsive Probes for 19F MRS/MRI Inflammation Imaging. Imaging Acute Organ Transplant Rejection with 19F MRI. Cardiac Disease. Monitoring of Specific Cell Populations. Tracking Lymphocytes in vivo. Tracking of Dendritic Cells. Neural Stem Cells. Pharmacology. Fluorinated Drugs and Natural Products. Other Biomedical Applications. Imaging of the Respiratory System. Tracking of Capsules and Catheters in the Human Gastrointestinal Tract. Perspectives. Perfluorocarbon Theranostic Nanomedicines: Pharmaceutical Scientist’s Perspective.