Information Resources in Toxicology (eBook)

Front Cover 1
Information Resources in Toxicology 4
Copyright Page 5
Contents 10
List of Contributors 24
Foreword 30
Preface 32
Preface to the Third Edition 34
Preface to the Second Edition 36
Preface to the First Edition 38
Annex 1: Some Toxicological Abbreviations used in This Book 40
Annex 2: Abbreviations of Some National and International Organizations and Miscellaneous Terms 42
PART I: The Discipline of Toxicology 44
CHAPTER 1 Toxicology: A Primer 46
CHAPTER 2 History of Toxicology 54
Highlights in the history of toxicology 54
CHAPTER 3 Development of Toxicoinformatics 74
Introduction 74
The realm of toxicology information 74
Background in toxicology information systems 79
The technology wave in toxicology information systems 81
Applications of toxicology information systems 84
Challenges ahead for toxicology information systems 87
Future directions 88
Summary 89
CHAPTER 4 Toxicoinformatics Today 92
Toxnet 92
Resources 92
PART II: Subject Categorization: Books and More 100
CHAPTER 5 General Texts 102
Resources 102
CHAPTER 6 Analytical Toxicology 110
Introduction 110
Resources 110
CHAPTER 7 Animals in Research 114
Introduction 114
Resources 114
CHAPTER 8 Biomarkers 118
Introduction 118
Resources 119
Other resources 126
CHAPTER 9 Biotechnology 130
Introduction 130
Information resources section 130
CHAPTER 10 Biotoxins 134
Introduction 134
Resources 134
CHAPTER 11 Cancer 146
Introduction 146
Resources 146
CHAPTER 12 Chemical Compendia 166
Introduction 166
Resources 166
CHAPTER 13 Chemicals: Cosmetics and Other Consumer Products 172
Introduction 172
Resources 172
CHAPTER 14 Drugs 176
Introduction 176
Resources 176
CHAPTER 15 Chemicals: Dusts and Fibers 186
Introduction 186
Resources 186
CHAPTER 16 Chemicals: Metals 190
Introduction 190
Resources 190
CHAPTER 17 Chemicals: Pesticides 194
Introduction 194
Resources 195
CHAPTER 18 Chemicals: Solvents 210
Introduction 210
Resources 211
CHAPTER 19 Chemicals: Selected Chemicals 218
Introduction 218
Resources 218
CHAPTER 20 Clinical Toxicology and Clinical Analytical Toxicology 226
Introduction 226
Resources 227
CHAPTER 21 Developmental and Reproductive Toxicology 230
Introduction 230
Resources 231
CHAPTER 22 Disaster Preparedness and Management 238
Introduction 238
Resources 240
CHAPTER 23 Environmental Toxicology: Aquatic 246
Introduction 246
Resources 247
CHAPTER 24 Environmental Toxicology: Air 260
Introduction 260
Resources 260
CHAPTER 25 Environmental Toxicology: Hazardous Waste 282
Introduction 282
Resources 282
CHAPTER 26 Environmental Toxicology: Terrestrial 290
Introduction 290
Resources 290
CHAPTER 27 Environmental Toxicology: Wildlife 294
Introduction 294
Resources 294
CHAPTER 28 Epidemiology 298
Introduction 298
Resources 299
CHAPTER 29 Ethical Considerations 306
Introduction 306
Resources 307
CHAPTER 30 Everyday Exposures 312
Introduction 312
Resources 313
CHAPTER 31 Food and Nutrition 324
Introduction 324
Resources 324
CHAPTER 32 Forensic Toxicology 336
Introduction 336
Resources 336
CHAPTER 33 Genetic Toxicology 340
Introduction 340
Resources 340
CHAPTER 34 Mixtures 350
Introduction 350
Resources 350
CHAPTER 35 Molecular, Cellular, and Biochemical Toxicology 356
Introduction 356
Resources 356
CHAPTER 36 Nanotechnology 364
Introduction 364
Resources 364
CHAPTER 37 Noise 372
Introduction 372
Resources 372
CHAPTER 38 Occupational Health 378
Introduction 378
Resources 379
CHAPTER 39 Genomics 388
Introduction 388
Resources 389
CHAPTER 40 Pathology 400
Introduction 400
Resources 400
CHAPTER 41 Pharmacokinetics and Metabolism 408
Introduction 408
Resources 408
CHAPTER 42 Physical Hazards 414
Physical hazards in general 414
Resources 416
CHAPTER 43 Precautionary Principle 430
Introduction 430
Resources 432
CHAPTER 44 Radiation 438
Introduction 438
Resources 438
CHAPTER 45 Regulatory Toxicology 444
Introduction 444
Resources 444
CHAPTER 46 Risk Assessment 450
Introduction 450
Resources 452
CHAPTER 47 Target Sites: General 466
Introduction 466
Resources 466
CHAPTER 48 Target Sites: Cardiovascular 474
Introduction 474
Resources 474
CHAPTER 49 Target Sites: Endocrine 478
Introduction 478
Resources 479
CHAPTER 50 Target Sites: Gastrointestinal 486
Resources 488
CHAPTER 51 Target Sites: Hematopoietic 490
Introduction 490
Resources 490
CHAPTER 52 Target Sites: Immune 494
Introduction 494
Resources 494
CHAPTER 53 Target Sites: Kidney 500
Introduction 500
Resources 500
CHAPTER 54 Target Sites: Liver 504
Introduction 504
Resources 504
CHAPTER 55 Target Sites: Nervous System 508
Introduction 508
Resources 508
CHAPTER 56 Target Sites: Respiratory 516
Introduction 516
Resources 516
CHAPTER 57 Target Sites: Sensory 522
Introduction 522
Resources 522
CHAPTER 58 Target Sites: Skin 524
Introduction 524
Resources 524
CHAPTER 59 Terrorism and Warfare (Chemical, Biological, Radioactive, and Nuclear) 528
Introduction 528
Resources 530
CHAPTER 60 Testing Methods and Toxicity Assessment (Including Alternatives) 540
Introduction 540
Toxicity testing methods 541
Scientific information 544
Resources 544
CHAPTER 61 Veterinary Toxicology 558
Introduction 558
Resources 558
PART III: Other Resources Categorization 566
CHAPTER 62 Organizations 568
Introduction 568
Listing of organizations 569
Special groups 595
CHAPTER 63 Journals and Newsletters 600
Scientific journals 600
Resources 601
Additional journals carrying relevant articles 617
Newsletters 617
CHAPTER 64 General Interest and Popular Works 620
Introduction 620
The impact of Silent Spring and Rachel Carson – celebrating Carson's 100th birthday 621
Contemporary works 622
Defining a core list of 'widely held books' in libraries 628
Consumers' one stop resource: Channing Bete 631
Toxic fiction 631
Juvenile literature 632
CHAPTER 65 Technical Reports and Government Information 634
Introduction 634
The plight of the EPA libraries 635
Will the national agricultural library be next? 636
Technical report literature 637
National technical information service (NTIS) 638
National academies 641
Council on environmental quality 642
National toxicology program (NTP) 642
Government printing office 642
Library of congress 643
Locating the hard-to-find 643
Judicial and legal information 643
General accountability office 644
Identifying state, county, and local sources of technical reports 645
Non-governmental organization reports 646
CHAPTER 66 Audiovisual and Non-Print Resources 650
Introduction 650
Resources 650
PART IV: Internet and Digital Tools 654
CHAPTER 67 The Internet: Recent Trends 656
Introduction 656
Search engines 656
Tools for obtaining news 657
Blogs 657
Open access publishing 657
Podcasting 658
Wikis 658
Social networking 659
Semantic web 659
CHAPTER 68 Web-Based Databases 662
Introduction 662
Databases with a focus on toxicology and related subjects 662
State information 669
Focus on toxicogenomics 669
Scientific databases containing toxicology information 672
CHAPTER 69 Software Tools for Toxicology and Risk Assessment 674
Introduction 674
QSAR tools 674
The broad universe of QSARs 674
QSAR applications for chemical screening, prioritization, and regulatory and corporate decision-making 675
QSAR reliability and validity 675
QSAR applications 675
International uses of QSARs by regulatory authorities 676
Key QSAR Websites 679
Non-QSAR-Related software tools 679
Statistical and risk forecasting tools 680
PART V: Special Topics 682
CHAPTER 70 The Legal and Regulatory Framework 684
Introduction 684
Chemicals vs products and regulatory authorities 684
Laws, agencies, and regulations 685
'Safe' lists 689
Compliance 689
Regulation development 689
Information resources 691
CHAPTER 71 Hazard Communication 696
Introduction 696
Background 696
What is the core of hazard communication? 697
What is the first step in communicating hazards? 697
What is an MSDS? 697
What resources are needed? 698
Are there other resources for hazard communication? 698
CHAPTER 72 Professional Education 708
Introduction 708
Careers and education in toxicology 709
Continuing education for professionals 722
CHAPTER 73 Public Education 724
Introduction 724
K-12 educational resources 725
Public education resources 730
Environmental justice resources 730
Spanish resources 732
CHAPTER 74 Grants and Funding 734
Introduction 734
Grantsmanship: The art of getting funded 735
Finding funds and grants 736
Standard grant and funding reference resources 737
Internships and scholarships 738
Additional select web-based grant-finding resources 740
CHAPTER 75 Poison Control Centers 744
Introduction 744
History 744
Poison centers 744
Poison information service 745
Clinical treatment/intensive care units 745
The assessment of poisonings 745
Poisoning Severity Score 745
Notifications of poisonings in Germany 746
Reported cases 746
Assessment of poisonings 747
Reports on poisonings 752
Links/literature 752
CHAPTER 76 Patents 754
Introduction 754
Resources 755
PART VI: The Global Arena 760
CHAPTER 77 Overview of International Activities 762
Introduction 762
International activities 762
Intergovernmental organizations 769
Main features of EC chemicals legislation 770
CHAPTER 78 Introduction to Country Chapters 780
CHAPTER 79 European Union 782
Introduction 782
Websites 784
CHAPTER 80 Australia 786
Introduction 786
Resources 788
CHAPTER 81 Brazil 810
Introduction 810
Resources 811
CHAPTER 82 Canada 824
Introduction 824
Resources 824
The regulation of chemicals in Canada 838
CHAPTER 83 Chile 856
Introduction 856
Resources 856
CHAPTER 84 China 860
Introduction 860
Historical evolution on chinese society of toxicology (CST) 861
Resources 864
CHAPTER 85 Czech Republic 878
History of Toxicology in the Czech Republic 878
Resources 880
CHAPTER 86 Denmark 896
Introduction 896
Resources 901
Databases 903
CHAPTER 87 Ecuador 910
Introduction 910
Resources 911
CHAPTER 88 Finland 918
Introduction 918
Resources 919
CHAPTER 89 France 934
Introduction 934
Resources 935
CHAPTER 90 Germany 942
Introduction 942
Resources 943
CHAPTER 91 India 956
Introduction 956
Resources 956
CHAPTER 92 Iran 988
Toxicology in Iran 988
Resources 989
Acknowledgment 999
CHAPTER 93 Israel 1000
Introduction 1000
Resources 1000
CHAPTER 94 Italy 1010
Introduction 1010
Resources 1010
CHAPTER 95 Japan 1034
Introduction 1034
Toxicology in Japan 1034
Resources 1037
CHAPTER 96 Malaysia 1056
Introduction 1056
Resources 1056
CHAPTER 97 Mexico 1066
Introduction 1066
Resources 1066
Acknowledgments 1078
CHAPTER 98 The Netherlands 1080
Short history of toxicology in The Netherlands 1080
Resources 1081
Acknowledgments 1092
CHAPTER 99 Norway 1094
Introduction 1094
Resources 1095
CHAPTER 100 Poland 1104
Introduction 1104
Resources 1105
CHAPTER 101 Russia 1124
History and current state of toxicology in Russia 1124
State registration of chemical and biological substances in the Russian federation 1125
Resources 1125
CHAPTER 102 South Africa 1142
Introduction 1142
Resources 1142
CHAPTER 103 Spain 1168
Introduction 1168
Resources 1169
CHAPTER 104 Sweden 1190
Introduction 1190
Historical notes in Swedish toxicology 1190
Toxicology becomes organized 1191
CHAPTER 105 Taiwan 1208
Introduction 1208
Resources 1208
CHAPTER 106 United Kingdom 1220
Introduction 1220
Resources 1221
CHAPTER 107 Uruguay 1256
Introduction 1256
Resources 1257
Universities 1260
CHAPTER 108 Venezuela 1262
Toxicology in Venezuela 1262
Resources 1265
Organizations (Government) 1267
Organizations (Non-Governmental) 1269
APPENDIX I: Toxicology Data and Information Management 1274
APPENDIX II: Glossary of Terms used in Toxicology, 2nd Edition 1294
PREFACE 1297
ACKNOWLEDGMENTS 1298
ALPHABETICAL ENTRIES 1299
A 1299
B 1306
C 1311
D 1319
E 1322
F 1328
G 1329
H 1331
I 1335
J 1338
K 1338
L 1339
M 1341
N 1347
O 1349
P 1351
Q 1358
R 1358
S 1363
T 1370
U 1374
V 1375
W 1375
X 1376
Y 1376
Z 1376
ANNEX 1: ABBREVIATIONS AND ACRONYMS USED IN TOXICOLOGY LITERATURE 1377
ANNEX 2: ABBREVIATIONS AND ACRONYMS OF NAMES OF INTERNATIONAL BODIES AND LEGISLATION 1380
ANNEX 3: CLASSIFICATION OF CARCINOGENICITY 1382
APPENDIX III: Toxicological Quotations: Famous, Infamous, Obscure 1386
Index 1392
A 1392
B 1403
C 1424
D 1441
E 1450
F 1460
G 1466
H 1472
I 1477
J 1483
K 1488
L 1490
M 1493
N 1502
O 1509
P 1513
Q 1521
R 1521
S 1527
T 1536
U 1544
V 1547
W 1549
X 1552
Y 1553
Z 1553