Lung (eBook)

Development, Aging and The Environment

Richard Harding, Kent Pinkerton, Charles Plopper (Herausgeber)

eBook Download: PDF

2003 | 1. Auflage
424 Seiten
Elsevier Science (Verlag)
978-0-08-048135-7 (ISBN)

This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment.

* Discusses the mechanisms that regulate the initial events of lung morphogenesis
* Provides a better understanding of the cellular and biochemical events involved in alveolarization
* Development of the pulmonary immune system and how the exposure to allergens during development may lead to diseases such as asthma

This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment.* Discusses the mechanisms that regulate the initial events of lung morphogenesis * Provides a better understanding of the cellular and biochemical events involved in alveolarization* Development of the pulmonary immune system and how the exposure to allergens during development may lead to diseases such as asthma

Front Cover 1
The Lung: Development, Aging and the Environment 4
Copyright Page 5
Contents 6
Preface 8
List of Contributors 10
Introduction 14
Part I: Critical Events in Normal Lung Development and Aging 16
Chapter 1. Lung Morphogenesis, Role of Growth Factors and Transcription Factors 18
Chapter 2. Development of Airway Epithelium 28
Chapter 3. Development of the Airway Innervation 48
Chapter 4. Development of Alveoli 70
Chapter 5. Development of the Pulmonary Basement Membrane Zone 90
chapter 6. Development of the Pulmonary Vasculature 96
Chapter 7. Developmental Physiology of the Pulmonary Circulation 120
Chapter 8. Development of Fluid Transport Across Pulmonary Epithelia 134
Chapter 9. Physical, Endocrine and Growth Factors in Lung Development 146
Chapter 10. Development of the Pulmonary Surfactant System 164
Chapter 11. Development of the Pulmonary Immune System 184
Chapter 12. Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems 192
Chapter 13. Compensatory Lung Growth: Relationship to Postnatal Lung Growth and Adaptation in Destructive Lung Disease 202
Chapter 14. Pulmonary Transition at Birth 216
Chapter 15. Normal Aging of the Lung 228
Part II: Environmental Influences on Lung Development and Aging 250
Chapter 16. Pulmonary Consequences of Preterm Birth 252
Chapter 17. Role of Nutrition in Lung Development Before and After Birth 268
Chapter 18. Influence of High Altitude on Lung Development and Function 282
Chapter 19. Genetic Factors Involved in Susceptibility to Lung Disease 292
Chapter 20. Effects of Environmental Tobacco Smoke on Lung Development 306
Chapter 21. Nicotine Exposure During Early Development: Effects on the Lung 316
Chapter 22. Exposure to Allergens During Development 326
Chapter 23. Development of Atopy in Children 336
Chapter 24. Effects of Air Pollution on Lung Function Development and Asthma Occurrence 348
Chapter 25. Environmental Toxicants and Lung Development in Experimental Models 360
Chapter 26. Repair of Environmental Lung Injury During Development 368
Chapter 27. Effects of Aging, Disease and the Environment on the Pulmonary Surfactant System 378
Chapter 28 Environmental Determinants of Lung Aging 392
Index 412

Erscheint lt. Verlag	21.11.2003
Sprache	englisch
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Arbeits- / Sozial- / Umweltmedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
	Medizinische Fachgebiete ► Innere Medizin ► Pneumologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Naturwissenschaften ► Biologie
	Technik
ISBN-10	0-08-048135-3 / 0080481353
ISBN-13	978-0-08-048135-7 / 9780080481357

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