Agrobacterium: From Biology to Biotechnology

Dr. Tzvi Tzfira is an Assistant Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan. Dr. Vitaly Citovsky is a Professor in the Department of Biochemistry and Cell Biology at Stony Brook University.

Agrobacterium: A disease-causing bacterium.- A Brief History of Research on Agrobacterium Tumefaciens: 1900–1980s.- Agrobacterium and Plant Biotechnology.- The Agrobacterium Tumefaciens C58 Genome.- Agrobacterium—Taxonomy of Plant-Pathogenic Rhizobium Species.- The Initial Steps in Agrobacterium Tumefaciens Pathogenesis: Chemical Biology of Host Recognition.- Agrobacterium-Host Attachment and Biofilm Formation.- Production of a Mobile T-DNA by Agrobacterium Tumefaciens.- Translocation of Oncogenic T-DNA and Effector Proteins to Plant Cells.- Intracellular Transport of Agrobacterium T-DNA.- Mechanisms of T-DNA integration.- Agrobacterium Tumefaciens-Mediated Transformation: Patterns of T-Dna Integration Into the Host Genome.- Function of Host Proteins in The Agrobacterium-Mediated Plant Transformation Process.- The Oncogenes of Agrobacterium Tumefaciens and Agrobacterium Rhizogenes.- Biology of Crown Gall Tumors.- The Cell-Cell Communication System of Agrobacterium Tumefaciens.- Horizontal Gene Transfer.- Agrobacterium-Mediated Transformation of Non-Plant Organisms.- The Bioethics and Biosafety of Gene Transfer.- Agrobacterium-Mediated Gene Transfer: A Lawyer’s Perspective.