Bone Tumours in Man and Animals -  L. N. Owen

Bone Tumours in Man and Animals (eBook)

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2014 | 1. Auflage
214 Seiten
Elsevier Science (Verlag)
978-1-4831-6307-9 (ISBN)
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Bone Tumours in Man and Animals covers advances in the understanding of the pathogenesis of bone neoplasia in humans and animals as well as their diagnosis and treatment. In the case of animals, particular emphasis is placed on dogs. This book is comprised of 15 chapters and begins by introducing the reader to the principles of diagnosis, including biopsy and bone scanning, and methods of treatment employed for bone tumors in human and animal patients, including surgery, radiotherapy, and chemotherapy. The following chapters focus on bone cysts and benign tumors of osseous origin; osteosarcoma in humans and animals such as dogs, cats, and mice; and tumors of cartilaginous origin such as solitary enchondroma, enchondromatosis, chondroblastoma, and chondromyxoid fibroma. Tumors arising from fibrous, fatty, neurological, or undifferentiated connective tissue are also considered, along with those arising from bone marrow or lymphoid tissue. This book concludes by offering suggestions for future research. This text is intended for clinicians, radiologists, and pathologists, both medical and veterinary, as well as for biologists, biochemists, and radiation physicists.
Bone Tumours in Man and Animals covers advances in the understanding of the pathogenesis of bone neoplasia in humans and animals as well as their diagnosis and treatment. In the case of animals, particular emphasis is placed on dogs. This book is comprised of 15 chapters and begins by introducing the reader to the principles of diagnosis, including biopsy and bone scanning, and methods of treatment employed for bone tumors in human and animal patients, including surgery, radiotherapy, and chemotherapy. The following chapters focus on bone cysts and benign tumors of osseous origin; osteosarcoma in humans and animals such as dogs, cats, and mice; and tumors of cartilaginous origin such as solitary enchondroma, enchondromatosis, chondroblastoma, and chondromyxoid fibroma. Tumors arising from fibrous, fatty, neurological, or undifferentiated connective tissue are also considered, along with those arising from bone marrow or lymphoid tissue. This book concludes by offering suggestions for future research. This text is intended for clinicians, radiologists, and pathologists, both medical and veterinary, as well as for biologists, biochemists, and radiation physicists.

Front Cover 1
Bone Tumours in Man and Animals 4
Copyright Page 5
Table of Contents 8
PREFACE 10
ACKNOWLEDGEMENTS 11
CHAPTER 1. PRINCIPLES OF DIAGNOSIS 14
CLINICAL 14
RADIOGRAPHY 15
ARTERIOGRAPHY 17
BONE SCANNING 18
THERMOGRAPHY 18
BIOPSY 19
HISTOLOGICAL EXAMINATION 20
HAEMATOLOGY AND SERUM ENZYMES 21
TETRACYCLINE AND RADIOACTIVE FIBRINOGEN LOCALIZATION 23
REFERENCES 23
CHAPTER 2. METHODS OF TREATMENT 25
SURGERY 25
RADIOTHERAPY 26
CHEMOTHERAPY 28
HORMONES 29
IMMUNE MECHANISMS 29
ULTRASOUND AND LASER RADIATION 30
SPONTANEOUS REGRESSION OF CANCER 30
RELIEF OF PAIN 31
CAUSES OF DEATH IN BONE CANCER 31
REFERENCES 31
CHAPTER 3. BONE CYSTS AND BENIGN TUMOURS OF OSSEOUS ORIGIN 33
BONE CYSTS 33
BENIGN TUMOURS OF OSSEOUS ORIGIN 37
REFERENCES 40
CHAPTER 4. OSTEOSARCOMA IN MAN AND DOG 42
INCIDENCE AND SITE 42
METASTASIS 48
OSTEOSARCOMA ARISING IN DISEASED BONE 50
DIAGNOSIS 51
RADIOGRAPHIC APPEARANCE 51
PATHOLOGY 54
HISTOLOGY 56
TREATMENT 59
REFERENCES 62
CHAPTER 5. OSTEOSARCOMA IN OTHER SPECIES 66
CAT 66
MOUSE 66
REFERENCES 72
CHAPTER 6. TUMOURS OF CARTILAGINOUS ORIGIN 75
SOLITARY ENCHONDROMA 75
ENCHONDROMATOSIS 75
BENIGN CHONDROBLASTOMA 77
CHONDROMYXOID FIBROMA 78
UNCLASSIFIED CHONDROMAS OF BONE IN ANIMALS 78
MULTIPLE CARTILAGINOUS EXOSTOSES (DIAPHYSIAL ACLASIS) 83
CHONDROSARCOMA 85
REFERENCES 91
CHAPTER 7. TUMOURS ARISING FROM FIBROUS, FATTY, NEUROLOGICAL OR UNDIFFERENTIATED CONNECTIVE TISSUE 93
FIBROUS CORTICAL DEFECT AND NON-OSTEOGENIC FIBROMA OF BONE 93
LIPOMA 100
LIPOSARCOMA 101
NEURILEMMOMA 105
NEUROFIBROMA 105
GIANT-CELL TUMOUR OR OSTEOCLASTOMA 106
REFERENCES 109
CHAPTER 8. TUMOURS ARISING FROM VASCULAR, SYNOVIAL OR EMBRYONIC VESTIGIAL TISSUE. HETEROPLASIAS 112
HAEMANGIOMA 112
MALIGNANT HAEMANGIO-ENDOTHELIOMA (ANGIOSARCOMA, HAEMANGIOSARCOMA) 112
HAEMANGIOPERICYTOMA (GLOMUS TUMOUR) 113
SYNOVIOMA (XANTHOMA, BENIGN GIANT-CELL SYNOVIOMA) 115
MALIGNANT SYNOVIOMA 116
CHORDOMA 120
ADAMANTINOMA (AMELOBLASTOMA) 121
' AMELOBLASTOMA ' OF LONG BONES 123
REFERENCES 124
CHAPTER 9. TUMOURS ARISING FROM BONE MARROW OR LYMPHOID TISSUE 127
PLASMA-CELL MYELOMA 127
MALIGNANT LYMPHOMA AND RETICULUM-CELL SARCOMA 133
ACUTE LEUKAEMIA 134
HODGKIN'S DISEASE 135
HISTIOCYTOSIS X 135
BURKITTS TUMOUR (AFRICAN LYMPHOMA) 135
EWING'S TUMOUR 138
REFERENCES 139
CHAPTER 10. TUMOURS METASTATIC TO THE SKELETON 142
ROUTES OF SPREAD 142
OCCURRENCE 143
RADIOGRAPHY 146
PATHOLOGY 149
TREATMENT 150
REFERENCES 151
CHAPTER 11. TUMOURS INDUCED BY EXTERNAL IRRADIATION 153
MAN 153
ANIMALS 155
REFERENCES 158
CHAPTER 12. TUMOURS INDUCED BY INTERNAL IRRADIATION 161
INTRODUCTION 161
MAN 162
MICE 163
RATS 166
RABBITS 169
DOGS 174
PIGS 177
CATS 180
MONKEYS 180
REFERENCES 180
CHAPTER 13. CHEMICAL, VIRAL AND OTHER METHODS OF TUMOUR INDUCTION 185
CHEMICAL 185
PLASTIC FILMS AND OTHER METHODS 192
VIRAL 192
REFERENCES 195
CHAPTER 14. TRANSPLANTABLE TUMOURS 198
REFERENCES 203
CHAPTER 15. SOME SUGGESTIONS FOR FUTURE RESEARCH 206
INDEX 210

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