Clinical Applications of Mass Spectrometry in Drug Analysis

Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology.- Quantitative LC-MS/MS Analysis of Amphetamines and Cocaine in Human Urine.- Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serum Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Turbulent Flow Liquid Chromatography-Tandem Mass Spectrometry Methods for Antiepileptic Drug Quantitation in Serum.- Quantitative LC-MS/MS Method for the Simultaneous Measurement of Six Antiepileptics and Pentobarbital in Human Serum.- Triazole Antifungal Quantification for Therapeutic Drug Monitoring in Serum by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS):  Posaconazole, Voriconazole, Itraconazole, and Hydroxyitraconazole.- Liquid Chromatography-Tandem Mass Spectrometry-Based Therapeutic Monitoring of Plasma Atovaquone Concentrations in Pediatric Patients.- Analysis of Barbiturates in Urine by LC-MS/MS.- High Throughput Quantitative LC-MS/MS Analysis of Barbiturates in Human Urine.- High Throughput Quantitative LC-MS/MS Analysis of Benzodiazepines in Human Urine.- Quantitation of Bupropion in Urine by Liquid Chromatography-Tandem Mass Spectrometry.- Quantitative Analysis of Buprenorphine, Norbuprenorphine, and Their Glucuronide Metabolites in Human Urine.- Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Plasma Busulfan.- Determination of Busulfan and Melphalan in Plasma by Turbulent Flow Chromatography-Tandem Mass Spectrometry.- Serum and Urine Quantification of Delta-8 and Delta-9 Tetrahydrocannabinol Carboxylic Acid Using Gas Chromatography-Mass Spectrometry.- 11-Nor-9-Carboxy-Δ8-Tetrahydrocannabinol, 7-Carboxy Cannabidiol, and 11-Nor-9-Carboxy-Δ9-Tetrahydrocannabinol in Urine by LC-MS/MS.- Quantification of Clofarabine and Fludarabine in Plasma by High Performance Liquid Chromatography-Tandem Mass Spectrometry.- Untargeted High-Resolution Mass Spectrometry for Detection of Natural Products and Confiscated Powders and Pills.- Drug Screening of 49 Compounds by Liquid Chromatography-Tandem Mass Spectrometry in Saliva.- High Throughput Comprehensive Quantitative LC-MS/MS Analysis of a Common Drugs and Metabolites (62 Compounds) in Human Urine.- Detection of 41 Drugs and Metabolites in Urine with Internal Hydrolysis Control by Liquid Chromatography-Tandem Mass Spectrometry.- Comprehensive Urine Drug Screen by Gas Chromatography-Mass Spectrometry (GC-MS).- Comprehensive Urine Drug Screen by Liquid Chromatography-Quadrupole Time of Flight Mass Spectrometry.- A Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Ethyl Glucuronide and Ethyl Sulfate in Urine.- Quantification of Fentanyl and Norfentanyl in Whole Blood Using Liquid Chromatography-Tandem Mass Spectrometry.- Quantitative Assay of Fentanyl and Analogues Using LC-MS/MS.- Analysis of Hypoglycemic Drugs by Liquid Chromatography-Tandem Mass Spectrometry.- Multiplex Immunosuppressant (ISD) Method for the Measurement of Cyclosporine A, Tacrolimus, Sirolimus/Rapamycin, and Everolimus in Whole Blood Using MassTrakTM Kit.- Assessment of Iohexol Serum Clearance by LC-MS/MS with Isotopically Labeled Internal Standard.- Quantification of Mycophenolic Acid in Plasma by High Performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Quantitation of Urine Nicotine, Cotinine, and 3-OH-Cotinine by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Quantification of Olanzapine by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Quantitative Opiate, Opioid, and Benzodiazepine Testing by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Quantitative LC-MS/MS Analysis of Opiates and Opioids in Human Urine.- Quantification of Oxcarbazepine Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Liquid Chromatography-Tandem Mass Spectrometry for Quantitation of Serum Pentobarbital.- Quantification of Phencyclidine (PCP) in Urine, Serum, or Plasma by Gas Chromatography-Mass Spectrometry (GC-MS).- Simultaneous Determination of Prednisone and Prednisolone in Serum by Turbulent Flow Liquid Chromatography-Tandem Mass Spectrometry.- Measurement of ThioTEPA and Its Metabolite TEPA in Plasma and Cerebrospinal Fluid by Turbulent Flow Chromatography-Tandem Mass Spectrometry.- A Direct Dilute and Shoot HPLC-MS/MS Method for Tetrahydrocannabinol (THC) Metabolites.- Quantification of Thiopurine Metabolites in Human Erythrocytes by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).- Determination of Treosulfan and Fludarabine in Plasma by Turbulent Flow Liquid Chromatography-Tandem Mass Spectrometry (TFLC-MS/MS).- Determination of Thiopurine S-Methyltransferase (TPMT) Activity in Human Erythrocytes by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).