Vascular Growth Factors and Angiogenesis

This volume focuses on a family of growth factors and their receptors known as vascular endothelial growth factor (VEGFs). VEGFs are critical for endothelial cell function, both during physiological and pathological conditions. Thus, tumours depend on VEGF in order to promote ingrowth of blood vessels. Without VEGF, blood vessels will not form. There is a growing awareness that deregulated production or action of VEGF is initiating a large number of diseases. This book is written by scientists in the field for an audience with medical or life science background. The contributors present an overview of knowledge in the area of VEGF receptor structure and function in a series of reviews spanning from molecular signal transduction and cellular biology to the clinic.