Bacterial Infection: Close Encounters at the Host Pathogen Interface

There are ominous signs that our defences against bacterial infections are crumbling. The past years have seen the emergence of superior pathogens that can no longer be controlled by antibiotics. We are in a race against microbial invaders. The challenge is to anticipate and respond to developments that affect the precarious balance between man and microbe. This volume presents articles from leading authorities on the frontiers of research probing molecular mechanisms of bacterial pathogenicity. Like many other areas of virology and medicine, this field has undergone a molecular and genetic revolution. Novel techniques and concepts are laying the groundwork for important advances in the control of bacterial disease.
TOC: From the contents: In vivo Gene Expression.- New Insights Into the Genetics and Regulation of Expression of Clostridium perfringens Enterotoxin.- Mechanisms of Pathogenesis of Staphylococcal/ Streptococcal Superantigens.- Intracellular Multiplication of Legionelle pneumophila.- Anthrax Pathogenesis and Host Response.- Identification of Virulence Determinants in Pathogenic Mycobacteria.- Fe(III)Periplasm-to-Cytosol Transporters of Gram-Negative Pathogens.- Molecular Pathogenesis of Urinary Tract Infections.