Advances in Ocular Toxicology

Welcome and Opening of Congress.- 1. Cytochrome P450 and Arachidonic Acid Metabolism in the Corneal Epithelium: Role in Inflammation.- 2. The Effects of 12(R)HETE and Its Metabolite 8(R)HHDTrE on Corneal Endothelial Function.- 3. Protein-Thiol Mixed Disulfides and Thioltransferase in the Lens: A Review…..- 4. Corneal Lesions in Beagle Dogs Given Oral 5-Ethynyluracil Followed by 5-Fluorouracil.- 5. Corneal Damage following Continuous Infusion in Rats: Possible Explanation and Preventative Measures.- 6. Ultraviolet Light-Induced Damage in Rabbit Corneal Epithelial Cellsin VitroProtection with Absorption Filters.- 7. The Effects ofad Libitum(AL) Overfeeding and Moderate Dietary Restriction (DR) on the Incidence of Spontaneous Corneal Dystrophy in Control Sprague-Dawley (SD) Rats.- 8. Barotoxic Effects on Morphology and Viability of Trabecular Cells: A Preliminary Report.- 9. Topical Fluorescein Application Can Induce Iritis and Glaucoma: An Unusual Case Report.- 10. Ocular Toxicity of Sodium Diethylthiocarbamate, DDTC, in the Beagle Dog.- 11. Do Therapeutic Doses of Ethambutol Cause Optic Nerve Toxicity?.- 12. Testing of Ocular Viscoelastics by Injection into the Rabbit Vitreous: Historical Control Data Resulting from Various Dosing Techniques.- 13. Effects of Antiviral Agents on Retinal Function in Vertebrate Retina.- 14. Experimental Implantation of Devices for Electrical Retinal Stimulation in Rabbits: Preliminary Results.- 15. Nitric Oxide in Ocular Inflammation.- 16. Role of Nitric Oxide in Vascular Dysfunction Associated with Ocular Diseases.- 17. Effects of the Inhibition of Nitric Oxide Synthase and Lipoxygenase on the Development of Endotoxin-Induced Uveitis.- 18. Evaluation of Two Rabbit Ocular Implantation Models Using Polymethylmethacrylate IntraocularLenses.- 19. Characterization of Immortalized Lens Epithelial Cells as a Potentialin VitroAlternative Model for the Cellular Toxicity and the Efficacy Evaluations of Ocular Drug Candidates.- 20. Immortalization and Characterizations of Rabbit Corneal Epithelial Cell Lines as Potentialin VitroAlternative Models for Evaluating the Cellular Toxicity of Ocular Drug Candidates.- 21. Comparison of Somein VitroMeasurements of Membrane Damage to Corneal Epithelial Cells.- 22. Computer-Assisted Evaluation of Iris Color Changes in Primate Toxicity Studies.- 23. Workshop onin Vitroversusin VivoModels for Ocular Toxicity Testing.- 24. Toxicity Testing for Ocular Drug Products.- Participants.