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Bioseparation and Bioprocessing -

Bioseparation and Bioprocessing

A Handbook

Ganapathy Subramanian (Herausgeber)

Buch | Hardcover
XXVIII, 770 Seiten
2007 | 2., vollständig überarbeitete Auflage
Wiley-VCH (Verlag)
978-3-527-31585-7 (ISBN)
365,00 inkl. MwSt
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In this new edition of the only resource to systematically cover all post-production issues, over 70 % of the content is new or rewritten in line with the rapidly evolving technology in the field. By combining the experience of academic experts, managers from the pharmaceutical and biotech industry, as well as independent consultants, biological product recovery is viewed from every possible angle, including biosafety and regulatory issues.

Dr. Ganapathy Subramanian is a biotechnology consultant with over 30 years experience in both industry and academia, in the application and development of processing, purification methodologies and chromatographic systems for large-scale use in environmental science, food science, perfumery cosmetics and pharmaceuticals. He has also taught extensively in the area of food and medical technology. A chemistry graduate from Madras, India, Dr Subramanian was awarded his Doctorate from the University of Glasgow, for work on natural products, and his main research interests lie in the utilisation of natural material separation processes and bio-conversions. Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 10 years, he has been organizing conferences promoting the integration and sharing of knowledge between academia and industry.

VOLUME 1STRATEGY AND DEVELOPMENTProcess Development: when to start, when to stopStrategies in downstream processingBIOPROCESS AND EARLY DSPProcess Development and Optimization for Biotechnology Production -- Monoclonal AntibodiesDynamics of cellular response to recombinant protein overexpression in Esscherichia coliPREPARATIVE (CHROMATOGRAPHIC) METHODSIon Exchange Chromatography in Biopharmaceutical ManufacturingDisplacement chromatography of biomacromoleculesThe Purification of Biomolecules by Countercurrent ChromatographyContinuous chromatography in the down-stream processing of compounds from biotechnological and natural originContinuous Annular ChromatographyPrinciples of membrane separation processesAffinity PrecipitationVOLUME 2SPECIFIC BIOPROCESSES AND SEPARATION METHODSBiological fuel cellsRemoval and Analysis of Contaminants and ImpuritiesHigh throughput RNAi: Emerging technology for functional GenomicsDeveloping an Antibody Purification ProcessThe Many Ways to Purify Plasmis DNA -- Choosing the right purification strategy based on the downstream applicationAdvanced Fractionation methods and analysis for proteomics applicationsSAFETY, QUALITY CONTROL, VALIDATION AND REGUATORY CONSIDERATIONSBiosafetyThe Manufacture of Gene Therapy Products and Viral VaccinesThe Virus and Prion safety of BiopharmaceuticalsProtein Glycosylation: Analysis and CharacterizationHigh Throughput glycoanalysis for use in BioprocessingQuality Control of Impantable Drug Delivery Systems?ANALYTICAL METHODS AND TECHNOLOGIESPolymerase Chain Reaction: an Analytical Tool in BioprocessingElectrokinetic SeparationsCapillary Isoelectric Focusing Methods for Charge-Based Analysis of Biopharmaceuticals

Sprache englisch
Maße 170 x 240 mm
Gewicht 1828 g
Einbandart gebunden
Themenwelt Naturwissenschaften Chemie
Schlagworte Bioprozesstechnik • Bioseparationstechnik • Chromatographie • Membranseparation
ISBN-10 3-527-31585-3 / 3527315853
ISBN-13 978-3-527-31585-7 / 9783527315857
Zustand Neuware
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