Bacterial Carbonic Anhydrases

Dr. Claudiu T. Supuran received his BSc in chemistry from the Polytechnic University of Bucharest, Romania (1987) and PhD in chemistry at the same university in 1991. In 1990, he became Assistant and then Associate Professor of Chemistry at the University of Bucharest. He was Visiting Scholar at the University of Florida, Gainesville, United States, at Griffith University, Brisbane, Australia, and Visiting Professor at University of La Plata, Argentina. In 1995 he moved to the University of Florence, Italy, where he is currently Full Professor in the Department of Neuroscience, Psychology, Medicine and Child Health. His main research interests include design of enzyme inhibitors and activators, heterocyclic chemistry, chemistry of sulfonamides, sulfamates, and sulfamides, biologically active organo-element derivatives, QSAR studies, X-ray crystallography of metallo-enzymes, metal complexes with biologically active ligands (metal-based drugs), carbonic anhydrases, cyclooxygenases, serine proteases, matrix metalloproteinases, bacterial proteases, and amino acid derivatives among others. He has published more than 1900 papers in these fields.

1. Overview on bacterial CA genetic families
Clemente Capasso
2. Bacterial a-CAs
Giuseppina De Simone
3. Bacterial ß-CAs
Marta Ferraroni
4. Bacterial ?-CAs
Andrea Angeli
5. Bacterial ?-CAs
Clemente Capasso
6. Sulfonamide bacterial CA inhibitors
Alessio Nocentini
7. Non-sulfonamide bacterial CA inhibitors
Fabrizio Carta
8. Helicobacter pylori CA inhibition
Simone Carradori, Ilaria D'Agostino and Concettina La Motta
9. Neisseria gonorrhoea CA inhibition
Daniel Flaherty
10. Vancomycin resistant enterococci CA inhibition
Daniel Flaherty
11. Pseudomonas aeruginosa CA inhibition
Marianna M. A. Patrauchan
12. Mycobacterium tuberculosis CA inhibition
Seppo Seppo
13. Challenges for developing bacterial CA inhibitors as novel antibiotics
Claudiu T. Supuran