Reviews in Fluorescence 2004

Chris D. Geddes Ph.D., is an Associate Professor and Director of the Institute of Fluorescence, at the University of Maryland Biotechnology Institute, Medical Biotechnology Center in Baltimore, USA. He has a B.Sc. from Lancaster University in England and a Kodak funded Ph.D. in Physical Chemistry (fluorescence spectroscopy) from the University of Wales Swansea, UK. Dr Geddes is the Editor-in-Chief of the Journal of Fluorescence, and both the Editor and Founding editor of the Who's Who in Fluorescence and Annual Reviews in Fluorescence Volumes. He is also Executive Director of the Society of Fluorescence. Dr Geddes's research is based on the development and subsequent application of a wide variety of fluorescence based disciplines, such as multi-photon excitation, resonance energy transfer and more recently metal-enhanced fluorescence (also termed radiative decay engineering), to understanding biologically and industrially important systems and problems. The design, synthesis and characterization of new fluorophores and macromolecular protein-nanogold assemblies has recently led to the successful development of small molecule and sensing platforms for cyanide, TNT, glucose, fluoride and pH. Other research in Dr Geddes's Institute of Fluorescence involves developing non-invasive and continuous approaches for physiological glucose monitoring. Recently Dr Geddes has developed a range of highly-sensitive glucose sensing contact lenses that can monitor tear glucose levels ( 500 m), which track blood glucose levels which are 10-fold higher. Dr. J.R. Lakowicz is Professor of Biochemistry at the University of Maryland School of Medicine and Director of the Center for Fluorescence Spectroscopy. Dr. Lakowicz has published over 400 scientific articles, has edited numerous books, holds 16 issued patents, and is the sole author of the widely used text, Principles of Fluorescence Spectroscopy, also published by Kluwer Academic/Plenum Publishers, now in its Second Edition.

Arenedicarboximides as Versatile Building Blocks for Fluorescent Photoinduced Electron Transfer Saccharide Sensors.- Progress Towards Fluorescent Molecular Thermometers.- From Molecular Luminescence to Information Processing.- Zinc Fluorescent Probes for Biological Applications.- Use of Fluorescence Spectroscopy to Monitor Protein-Membrane Associations.- Application of Green Fluorescent Protein-Based Chloride Indicators for Drug Discovery by High-Throughput Screening.- Exploring Membrane Microdomains and Functional Protein Clustering in Live Cells With Flow and Image Cytometric Methods.- Recent Advances in Single Molecule Fluorescence Spectroscopy.- Applications of Distributed Optical Fiber Sensing: Fluorescent Assays of Linear Combinatorial Arrays.- Fluorescence Techniques in Biomedicine: From the Monitoring of Cell Metabolism to Image Processing in Cancer Detection.- Detection of Genomic Abnormalities by Fluorescence In Situ Hybridization.- Luminescent Semiconductor Quantum Dots Nanoassemblies for Biological Applications.- Phospholipid Main Phase Transition Assessed by Fluorescence Spectroscopy.- New Analysis of Single Molecule Fluorescence Using Series of Photon Arrival Times.- Semiconductor Lights Sources in Modulation Fluorometry Using Digital Storage Oscilloscopes.