World of the Cell with CD-ROM

Wayne M. Becker teaches cell biology at the University of Wisconsin, Madison. His interest in textbook writing grew out of notes, outlines, and problem sets that he assembled for his students, culminating in Energy and the Living Cell, a paperback text on bioenergetics published in 1977, and The World of the Cell, the first edition of which appeared in 1986. He earned all his degrees at the University of Wisconsin, Madison. All three degrees are in biochemistry, an orientation that is readily discernible in his textbooks. His research interests have been in plant molecular biology, focused specifically on the regulation of the expression of genes that encode enzymes of the photorespiratory pathway. His interests in teaching, learning, and research have taken him on sabbatical leaves at Harvard University, Edinburgh University, the University of Indonesia, the University of Puerto Rico, Canterbury University in Christchurch, New Zealand, and the Chinese University of Hong Kong. His honors include a Guggenheim Fellowship, a Chancellor's Award for Distinguished Teaching, and a Visiting Scholar Award from the Royal Society of London. Lewis J. Kleinsmith is a Professor of Molecular, Cellular, and Developmental biology at the University of Michigan, where he has served on the faculty since receiving his Ph.D. from Rockefeller University in 1968. His teaching experiences have involved courses in introductory biology, cell biology, and cancer biology, and his research interests have included studies of growth control in cancer cells, the role of protein phosphorylation in eukaryotic gene regulation, and the control of gene expression during development. Among his numerous publications, he is the author of Principles of Cell and Molecular Biology, first published in 1988, and several award-winning educational software programs. His honors include a Guggenheim Fellowship, the Henry Russell Award, a Michigan Distinguished Service Award, citations for outstanding teaching from the Michigan Students Association, a Thurnau Professorship, an NIH Plain Language Award, and a Best Curriculum Innovation Award from the EDUCOM Higher Education Software Awards Competition. Jeff Hardin received his Ph.D. in biophysics from the University of California, Berkeley, and pursued post-doctoral work at Duke University. In 1991 he joined the faculty of the Zoology Department at the University of Wisconsin, Madison, where he is currently an associate professor. His research interests center on how the cells move and change the shape of the embryo. Dr. Hardin's teaching is enhanced by his extensive use of video-microscopy and his Web-based teaching materials, which are used on many campuses in the United States and other countries. As part of his interest in teaching biology, Dr. Hardin has been involved in several teaching initiatives, including being a founding member of the University of Wisconsin system-wide instructional technology initiative known as BioWeb. He is currently faculty director of the Biocore Curriculum, a four-semester honors biology sequence for undergraduates. His teaching awards include a Lily Teaching Fellowship and a National Science Foundation Young Investigator Award.

1. A Preview of the Cell 2. The Chemistry of the Cell

3. The Macromolecules of the Cell

4. Cells and Organelles

5. Bioenergetics: The Flow of Energy in the Cell

6. Enzymes: The Catalysts of the Cell

7. Membranes: Their Structure, Function, and Chemistry

8. Transport Across Membranes: Overcoming the Permeability Barrier

9. Chemotrophic Energy Metabolism: Glycolysis and Fermentation

10. Chemotrophic Energy Metabolism: Aerobic Respiration

11. Phototrophic Energy Metabolism: Photosynthesis

12. Intracellular Compartments: The Endoplasmic Reticulum, Golgi Complex, Endosomes, Lysosomes, and Peroxisomes

13. Signal Transduction Mechanisms: I. Electrical Signals in Nerve Cells

14. Signal Transduction Mechanisms: II. Messengers and Receptors

15. Cytoskeletal Systems

16. Cellular Movement: Motility and Contractility

17. Beyond the Cell: Extracellular Structures, Cell Adhesion, and Cell Junctions

18. The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus

19. The Cell Cycle: DNA Replication, Mitosis, and Cancer

20. Sexual Reproduction: Meiosis and Genetic Recombination

21. Gene Expression: I. The Genetic Code and Transcription

22. Gene Expression: II. Protein Synthesis and Sorting

23. The Regulation of Gene Expression

24. Cancer [exact title TBD]

Glossary

Appendix   Microscopy