Current Thoughts on Dementia
Springer Verlag, Singapore
978-981-16-7608-6 (ISBN)
lt;p>This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies.
The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
Ghulam Md Ashraf is currently working as an Associate Professor at King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. He has received his PhD in Biochemistry from Aligarh Muslim University, India in 2010. Dr. Ashraf has to his credit 273 publications ranging from peer-reviewed journal articles, books, and book chapters published with scholarly publishers (total citations: 4618, h-index: 33, i10-index: 128). He has been involved in 19 research projects funded by various agencies of Saudi Arabia, and is associated with renowned professional societies like Royal Society of Medicine (Fellow), Royal Society of Biology (Member) and American Society for Biochemistry and Molecular Biology (Member). Dr. Ashraf’s current research work focuses on investigating the role of anti-diabetic drugs in pyschotic and dementia conditions. Dr. Ashraf is also involved in editorial capacity with many reputed journals like PLOS one, Scientific Reports, Current Neuropharmacology, Frontiers in Bioscience-Landmark, Neural Regeneration Research, Current Proteins and Peptides, Journal of Proteomics, to mention a few. Md. Sahab Uddin is a Registered Pharmacist and a Research Scholar in the Department of Pharmacy at Southeast University, Dhaka, Bangladesh. Md. Uddin’s research interest is how neuronal operation can be restored to abate Alzheimer’s dementia. He has published copious articles in peer-reviewed international scientific journals. Md. Uddin has been enlisted in the Stanford University Lists of World's Top 2% Influencing Researchers based on the citation impact from Scopus of the single calendar year 2019. He has also authored and edited several books related to neuropharmacology and neurodegenerative disorders. Md. Uddin also serves as a guest editor, editorial, and reviewer board member of numerous scholarly journals. He is an active ad-hoc reviewer for more than 50 journals and reviewed more than 200 papers. Md. Uddin is a member of many national and international professional bodies. Moreover, he is the Founder and Executive Director of the Pharmakon Neuroscience Research Network, an open innovation hub bringing together neuroscientists to advance brain health. He received his BPharm in 2014, securing a first position from the Department of Pharmacy, Southeast University, Bangladesh.
lt;p>Risk Factors
Apolipoprotein E (APOE)
Histone modifications, demethylation, and microRNA regulation
Triggering receptor expressed on myeloid cells 2 (TREM2)
Brain-derived neurotrophic factor (BDNF)
Bridging integrator 1 (BIN1)
Protein tyrosine phosphatase 1B (PTP1B)
Leptin signaling
Insulin signaling
Autophagic dysfunction
Ubiquitin-proteasome system dysfunction
Circadian dysfunction
Endoplasmic Reticulum Stress
Depression
Normal pressure hydrocephalus
Antiphospholipid antibodies
Sex hormones
Changes in blood factors
Infection-induced systemic inflammation
Microbiota
Abdominal visceral fat
Atypical microvascular morphology
Plasma exosomes spread
Changes in visual cortex
Obesity, dyslipidemia, hyperglycemia and hypertension
Environmental pollutions
Therapeutic Interventions
NMDA receptor antagonists
Calcium channel blockers
Catecholamine
Statins
Immunotherapy
Quitting smoking
Physical activity
Diet and nutrition
Natural products as promising drug candidates
Nanotechnological applications
Electroacupuncture
Repetitive transcranial magnetic stimulation
Transcranial direct current stimulation
Reminiscence therapy
Reality orientation therapy
Bright-light therapy
Snoezelen multi-sensory stimulation
Behavioral therapy
Brain-computer interface applications
Music therapy
Hypoxic-hyperoxic training
Cognitive rehabilitation
Cognitive creativity
Stem cell research
| Erscheinungsdatum | 09.07.2023 |
|---|---|
| Zusatzinfo | 1 Illustrations, black and white; XV, 624 p. 1 illus. |
| Verlagsort | Singapore |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Schlagworte | aging • Alzheimer's disease • dementia • Genetics • Mild Cognitive Impairment • therapeutics |
| ISBN-10 | 981-16-7608-9 / 9811676089 |
| ISBN-13 | 978-981-16-7608-6 / 9789811676086 |
| Zustand | Neuware |
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